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Research Topic

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Cell transplantation: relevance in understanding brain development and prospects in brain repair

Topic Editors:

Afsaneh Gaillard, University of Poitiers, INSERM U1084, France

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Cell replacement therapy has the potential to replace lost neurons in the diseased brain and following injuries to the central nervous system, in pathologies including Parkinson’s disease, Huntington's disease, ischemic brain damage and traumatic brain injury.
This Frontiers Research topic welcomes contributions from the general field of cell transplantation, with particular emphasis on the history of brain cell transplantation and related ethical concerns.
Related articles will deal with issues such as transplantation performed in newborn recipients, in attempts to determine the importance of extrinsic and intrinsic factors in the process of stem cell differentiation in view of neuronal transplantation. New methodological breakthroughs in stem cell proliferation/differentiation methodologies and in cell transplantation methods and procedures are also welcomed. A further focus includes transplantation in adult recipients to repair damaged neural circuitry.

Possible sections:
• History of brain cell transplantation
• Ethical concerns in brain cell transplantation
• Transplantation in the developing brain
• Transplantation in the adult brain
• Sources of cells for transplantation

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