Organic Salts: Tunable Materials for Analytical Applications
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1
Louisiana State University, United States
My research group has been exploring the scientific applications of room-temperature ionic liquids (RTILs) for several years. More recently, we have extended the range of these materials to include applications of similar solid phase materials, i.e. organic salts with melting points of solid phase ionic liquids (25 °C to 100 °C) up to organic salts with melting points of 250 °C. To contrast these new materials with RTILs, we have created the acronym, GUMBOS (Group of Uniform Materials Based on Organic Salts). These GUMBOS have the tunable properties frequently associated with RTILs, including tunable solubility, melting point, viscosity, thermal stability, hydrophobicity, and functionality. Thus, when taken in aggregate, GUMBOS allow production of solid phase materials which have a wide range of biomedical and other scientific applications. Our GUMBOS have led to applications in many areas including sensors, cancer therapy, novel approach to antibiotics, and production of tunable nanomaterials (nanoGUMBOS). In regard to nanomaterials (nanoGUMBOS), we believe that our methodology represents an extremely useful approach to production of tunable nanomaterials since our materials are designed and assembled for specific uses (task specific), rather than adapted for use as is done for many nanomaterials. Selected applications of ionic liquids and GUMBOS, including sensor applications and cancer therapy, will be highlighted in this talk. Particular emphasis will be placed on a possible new development for selective cancer therapy.
Acknowledgements
This material is based upon work supported by the National Science Foundation under Grant Nos. CHE-1307611 and CHE-1508726. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.
Keywords:
GUMBOS,
NanoGUMBOS,
Sensors,
Hemoglobin,
reactive oxygen species
Conference:
National Organization for the Professional Advancement of Black Chemists and Chemical Engineers (NOBCChE) 45th Annual Conference , Orlando, Florida, United States, 17 Sep - 20 Sep, 2018.
Presentation Type:
Oral Presentation
Topic:
Analytical Chemsitry
Citation:
Warner
IM and
Cong
M
(2019). Organic Salts: Tunable Materials for Analytical Applications.
Front. Chem.
Conference Abstract:
National Organization for the Professional Advancement of Black Chemists and Chemical Engineers (NOBCChE) 45th Annual Conference .
doi: 10.3389/conf.fchem.2018.01.00016
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Received:
08 Oct 2018;
Published Online:
17 Jan 2019.
*
Correspondence:
Dr. Isiah M Warner, Louisiana State University, Baton Rouge, United States, iwarner@lsu.edu