Event Abstract

Maintaining good memory performance in older age – manifestations in the aging brain

  • 1 Umea University, Sweden

Functional neuroimaging studies have revealed age-related changes in patterns of brain activity. However, most previous studies did not control for performance differences. Recent evidence shows that elderly with a high memory performance display a more “youth-like” activation pattern (Nagel et al., 2009). Here, based on recently collected functional imaging data from > 300 adults ranging in age between 25 – 80 years, we will present further evidence on the relation between high memory performance in advanced age and functional and structural brain characteristics. In keeping with our previous findings (Habib et al., 2007), we observed substantial heterogeneity within the elderly population with regard to memory performance. Preliminary analyses of the brain-imaging data revealed that cognitively high-performing elderly were more similar to younger adults in terms of brain structure and function. Thus, a minimum of age-related brain changes seems to characterize individuals who maintain high levels of cognitive performance in older age.

Keywords: Aging, fMRI

Conference: XI International Conference on Cognitive Neuroscience (ICON XI), Palma, Mallorca, Spain, 25 Sep - 29 Sep, 2011.

Presentation Type: Symposium: Oral Presentation

Topic: Symposium 22: Successful aging: a neurocognitive perspective

Citation: Nyberg L (2011). Maintaining good memory performance in older age – manifestations in the aging brain. Conference Abstract: XI International Conference on Cognitive Neuroscience (ICON XI). doi: 10.3389/conf.fnhum.2011.207.00592

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Received: 14 Nov 2011; Published Online: 28 Nov 2011.

* Correspondence: Dr. Lars Nyberg, Umea University, Umea, Sweden, lars.nyberg@diagrad.umu.se