Unique and shared roles of the posterior parietal and dorsolateral prefrontal cortex in cognitive functions
- Department of Neurobiology and Anatomy, Wake Forest University School of Medicine, Winston-Salem, NC, USA
The dorsolateral prefrontal cortex (PFC) and posterior parietal cortex (PPC) are two parts of a broader brain network involved in the control of cognitive functions such as working-memory, spatial attention, and decision-making. The two areas share many functional properties and exhibit similar patterns of activation during the execution of mental operations. However, neurophysiological experiments in non-human primates have also documented subtle differences, revealing functional specialization within the fronto-parietal network. These differences include the ability of the PFC to influence memory performance, attention allocation, and motor responses to a greater extent, and to resist interference by distracting stimuli. In recent years, distinct cellular and anatomical differences have been identified, offering insights into how functional specialization is achieved. This article reviews the common functions and functional differences between the PFC and PPC, and their underlying mechanisms.
Keywords: monkey, neurophysiology, neuron, principal sulcus, intraparietal sulcus, persistent activity, attention
Citation: Katsuki F and Constantinidis C (2012) Unique and shared roles of the posterior parietal and dorsolateral prefrontal cortex in cognitive functions. Front. Integr. Neurosci. 6:17. doi:10.3389/fnint.2012.00017
Received: 29 February 2012; Paper pending published: 27 March 2012;
Accepted: 16 April 2012; Published online: 03 May 2012.
Copyright: © 2012 Katsuki and Constantinidis. This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited.
*Correspondence: Christos Constantinidis, Department of Neurobiology and Anatomy, Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, NC 27157, USA. e-mail: email@example.com