The role of human parietal area 7A as a link between sequencing in hand actions and in overt speech production
- 1Section Structural Functional Brain Mapping, Department of Psychiatry, Psychotherapy, and Psychosomatics, Medical School, RWTH Aachen University, Aachen, Germany
- 2Research Centre Jülich, Institute of Neuroscience and Medicine (INM-1), Jülich, Germany
- 3Section Clinical and Cognitive Neurosciences, Department of Neurology, Medical School, RWTH Aachen University, Aachen, Germany
- 4JARA – Translational Brain Medicine, Jülich and Aachen, Germany
- 5Institute of Clinical Neuroscience and Medical Psychology, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany
Research on the evolutionary basis of the human language faculty has proposed the mirror neuron system as a link between motor processing and speech development. Consequently, most work has focused on the left inferior frontal cortex, in particular Broca’s region, and the left inferior parietal cortex. However, the direct link between planning of hand motor and speech actions has yet to be elucidated. Thus, the present study investigated whether motor sequencing of hand vs. speech actions has a common neural denominator. For the hand motor task, 25 subjects performed single, repeated, or sequenced button presses with either the left or right hand. The speech task was in analogy; the same subjects produced the syllable “po” once or repeatedly, or a sequence of different syllables (“po-pi-po”). Speech motor vs. hand motor effectors resulted in increased perisylvian activation including Broca’s region (left area 44 and areas medially adjacent to left area 45). In contrast, common activation for sequenced vs. repeated production of button presses and syllables revealed the effector-independent involvement of left area 7A in the superior parietal lobule (SPL) in sequencing. These data demonstrate that sequencing of vocal gestures, an important precondition for ordered utterances and ultimately human speech, shares area 7A, rather than inferior parietal regions, as a common cortical module with hand motor sequencing. Interestingly, area 7A has previously also been shown to be involved in the observation of hand and non-hand actions. In combination with the literature, the present data thus suggest a distinction between area 44, which is specifically recruited for (cognitive aspects of) speech, and SPL area 7A for general aspects of motor sequencing. In sum, the study demonstrates a previously underspecified role of the SPL in the origins of speech, and may be discussed in the light of embodiment of speech and language in the motor system.
Keywords: language, speech, aphasia, fMRI, broca, apraxia, repetition
Citation: Heim S, Amunts K, Hensel T, Grande M, Huber W, Binkofski F and Eickhoff SB (2012) The role of human parietal area 7A as a link between sequencing in hand actions and in overt speech production. Front. Psychology 3:534. doi: 10.3389/fpsyg.2012.00534
Received: 30 July 2012; Accepted: 12 November 2012;
Published online: 05 December 2012.
, UC Davis, USA Anna Simmonds
, Imperial College London, UK Roel M. Willems
, Donders Institute for Brain, Cognition and Behaviour, Netherlands Jonathan Henry Venezia
, University of California, Irvine, USA
Copyright: © 2012 Heim, Amunts, Hensel, Grande, Huber, Binkofski and Eickhoff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
*Correspondence: Stefan Heim, Department of Psychiatry, Psychotherapy and Psychosomatics, Medical School, RWTH Aachen University, Pauwelsstraße 30, 52074 Aachen, Germany. e-mail: email@example.com