Types of Articles Published in Frontiers

Tier 2:Frontiersin Neuroscience

Focused Review
The second tier journal Frontiers in Neuroscience publishes Focused Reviews on major discoveries democratically selected from top articles in the Frontiers in Neuroscience Specialty Journals. Focused Reviews are centred on the original discovery, place the discovery in a wider context and are no more than 5 printed pages. Focused Reviews should embody related research by the authors and by other researchers that demonstrate the wider implications of the research discovery. Focused Reviews are invited articles, peer-reviewed by the original reviewers implicated at the specialty level and edited by the Chief Editor of the Specialty Journal from which the discovery arose. Advanced copy-editors ensure readability and comprehensibility by the general audience across the neuroscience field. Focused Reviews receive a DOI, are citable, published in HTML and PDF format and submitted to PubMed for indexing. Authors are not required to pay a fee to publish a Focused Review.
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Frontiers Commentary
Frontiers in Neuroscience publishes Commentaries on important discoveries selected from top articles in the Frontiers in Neuroscience Specialty Journals. Frontiers Commentaries are centered on the discovery, place the discovery into a wider context and are no more than one printed page. Frontiers Commentaries are invited publications, written by the Associate Editor and/or Review Editors who edited the original article. Frontiers Commentaries receive a DOI, are citable, published in HTML and PDF format and submitted to PubMed for indexing. Authors are not required to pay a fee to publish a Frontiers Commentary.
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Highlight (coming up soon!)
Frontiers in Neuroscience website automatically highlights the first 5 lines of the democratically selected top peer-reviewed and non-peer reviewed Articles, such as Research Articles, Commentaries, Hypothesis and Theories, Perspectives, Technology Reports, and Book Reviews, Methods, Reviews, News, etc published in the Specialty Journals with links to the original articles.

News & Announcements (coming up soon!)
Any registered Frontiers user may make an announcement for an upcoming conference, events, acknowledgements of research awards and achievements, or institutional announcements on the Specialty Journal website. Announcements are not for job applications or announcements of open positions. Announcements are published immediately on submission on the Journal's website.

Tier 1: Frontiers Specialty Journals

Original Research Articles
Original Research Articles describe the results of original research, can be up to 12 pages long, are peer-reviewed, copy-edited, receive a DOI, are citable, published in PDF and HTML format and submitted to PubMed for indexing. Authors are required to pay a fee to publish an Original Research Article. Authors of articles that are amongst the top articles selected democratically by the Frontiers Evaluation System will be invited to write a Focused Review of their discovery to be published in Frontiers in Neuroscience.
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Hypothesis and Theory Articles
Hypothesis and Theory Articles present a scientific argument, synthesis, hypothesis or theory. Hypothesis and Theory Articles should be closely tied to empirical data, and provide novel insights into a significant question or issue. In addition, the argument or theory put forth in a Hypothesis and Theory Articles should lead to testable predictions. Hypothesis and Theory Articles can be up to 12 pages long, are peer-reviewed, copy-edited, receive a DOI, are citable, published in PDF and HTML format and submitted to PubMed for indexing. Authors are required to pay a fee to publish a Hypothesis and Theory Article. Top Hypothesis and Theory Articles democratically selected by the Frontiers Evaluation System will be highlighted on the Frontiers in Neuroscience webpage with a direct link to the article.
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Perspectives Article
Perspectives present a viewpoint on an important area of research. Perspectives focus on a specific field or subfield and discuss current advances and future directions. Perspectives may add personal insight and opinion to a field. Perspectives can be up to 5 pages long, are peer-reviewed, copy-edited, receive a DOI, are citable, published in PDF and HTML format and submitted to PubMed for indexing. Authors are required to pay a fee to publish a Perspective Article. Top Perspective Articles democratically selected by the Frontiers Evaluation System will be highlighted on the Frontiers in Neuroscience webpage with a direct link to the article.
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Methods Article (NEW!)
Methods Articles present a cutting-edge technology that opens new avenues for experimental investigation of important neurobiological questions. Methods manuscripts should include in the form of a brief statement: the experimental objectives, the limitations of current techniques, and a detailed protocol of the new technique. In addition, there should be some data to demonstrate the power of the technique. Methods Articles may add personal insight and opinion of the significance of the technology for a field. Methods Articles can be up to 12 pages long, are peer-reviewed, copy-edited, receive a DOI, are citable, published in PDF and HTML format and submitted to PubMed for indexing. Authors are required to pay a fee to publish a Methods Article. Top Methods Articles democratically selected by the Frontiers Evaluation System will be highlighted on the Frontiers in Neuroscience webpage with a direct link to the article.
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Review Article (NEW!)
Review articles cover topics that have seen significant development or progress in recent years with comprehensive depth, balanced perspective, intellectual insight, and broad general interest. Reviews do not merely recap the literature, but critique fundamental concepts, issues, and problems that define the field. Review Articles can be up to 12 pages long, are peer-reviewed, copy-edited, receive a DOI, are citable, published in PDF and HTML format and submitted to PubMed for indexing. Authors are required to pay a fee to publish a Review Article. Top Reviews democratically selected by the Frontiers Evaluation System will be highlighted on the Frontiers in Neuroscience webpage with a direct link to the article.
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Frontiers Commentary
Frontiers Commentaries call attention to Frontiers papers of particular note and are written by the Review Editors who refereed the concerning paper. Frontiers Commentaries are 1 printed page and may contain no more than one illustration, are peer-reviewed by the Associate Editors, receive a DOI, are citable, published in HTML and PDF format and submitted to PubMed for indexing. Authors (that is the submitting Review Editors) are not required to pay a fee to publish a Commentary. Top Commentaries democratically selected by the Frontiers Evaluation System will be highlighted on the Frontiers in Neuroscience webpage with a direct link to the article.
Please Contact the Frontiers Editorial Office at editorial.office@frontiersin.org for submitting a Frontiers Commentary
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General Commentary (NEW!)
General Commentaries call attention to any papers of particular note and can be submitted to any Frontiers Specialty journal for review. General Commentaries are 1 printed page and may contain no more than one illustration, are peer-reviewed by the Associate Editors, receive a DOI, are citable, published in HTML and PDF format and submitted to PubMed for indexing. Authors are not required to pay a fee to publish a Commentary. Top Commentaries democratically selected by the Frontiers Evaluation System will be highlighted on the Frontiers in Neuroscience webpage with a direct link to the article.
Please Contact the Frontiers Editorial Office at editorial.office@frontiersin.org for submitting a General Commentary
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Book Review
Book Reviews are 1 printed page and may contain no more than one illustration, are peer-reviewed by the Associate Editors, receive a DOI, are citable, published in HTML and PDF format and submitted to PubMed for indexing. Any registered Frontiers user may submit Book Reviews. Authors are not required to pay a fee to publish a Book Review. Top book reviews democratically selected by the Frontiers Evaluation System will be highlighted on the Frontiers in Neuroscience webpage with a direct link to the article.
Please Contact the Frontiers Editorial Office at editorial.office@frontiersin.org for submitting a Book Review.
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Opinion Article
Opinion Articles allow researchers to publish an opinion on the interpretation of facts, value of methods used, weaknesses and strengths of any scientific theory or on any topic relevant to the field of research. Opinion Articles allow maximum freedom of expression for researchers and are not peer-reviewed. Opinion Articles should not be more than 2 pages long. The articles are copy-edited, receive a DOI, are citable, and published in PDF and HTML format, but are not submitted to PubMed for indexing. Authors are not required to pay a fee to publish an Opinion Article. Top Opinion Articles selected by the Frontiers Evaluation System, will be highlighted on the Frontiers in Neuroscience webpage with a direct link to the article.
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Technology Report (NEW!)
Technology Reports provide a ½-1 page report on a new method or emerging technique for the specialty field. Technology Reports introduce the basic technical background of the method and evaluate the advantages and the limitations of the approach and its applications. Technology Reports are not reviewed, and do not receive a DOI, but are posted on the Specialty Journal website in HTML format. Any registered Frontiers user, including companies, may submit Technology Reports. Authors are not required to pay a fee to publish Technology Reports. Top Technology Reports democratically selected by the Frontiers Evaluation System will be highlighted on the Frontiers in Neuroscience webpage with a direct link to the report.
Please Contact the Frontiers Editorial Office at editorial.office@frontiersin.org for submitting a Technology Report
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Conference (NEW!)
The Frontiers Conference site accepts postings of and links to upcoming conferences, as well as conference proceedings. Any registered Frontiers user may make a posting free of charge.

News (coming up soon!)
Any registered Frontiers users may make a news announcement of an event, of research awards and achievements, or institutional news on the Specialty Journal website. Frontiers News is not for job applications or announcements of open positions. News are published immediately on submission on the Speciality Journal's website. Authors are not required to pay a fee to publish a News report. Top news democratically selected by the Frontiers Evaluation System will be highlighted on the Frontiers in Neuroscience webpage with a direct link to the news article.

Lecture (coming up soon!)
The Frontiers Lectures site accepts postings of and links to lectures given by researchers. Any registered Frontiers user may make a posting free of charge. Jobs & Positions (coming up soon!) Any registered users may make an announcement for open positions in their laboratory or institute or post a job search. Postings are published immediately upon submission free of charge.

Discussion & Debate (coming up soon!)
Any registered users may post a comment on any subject and raise any issue relevant to the speciality field. Postings are published immediately upon submission for of charge.

Job & Position (coming up soon!)
Any registered users may make an announcement for open positions in their laboratory or institute or post a job search. Postings are published immediately upon submission.

Quick Submission Checklist

For Focused Reviews, Original Research, Hypothesis and Theory, Perspectives, Opinion, Methods and Review Articles:

Please note that the corresponding and submitting author(s) MUST be registered with Frontiers before submitting the article, because the review process takes place online and requires a Frontiers account.

In order to submit an article, please first log into your personal Frontiers Account.

The submission process consists of the following steps:

Step 1: Select a journal and an Associate Editor. Select the submission type (i.e., type of article you submit)
Step 2: Provide article information such as title, running title, abstract and keywords.
Step 3: Add author and co-author names, emails and affiliations.
Step 4: Verify abstract proof.
Step 5: Edit cover letter.
Step 6: Upload files. It is obligatory to submit

• 1) a manuscript PDF file which contains all the images and tables.
• 2) the manuscript source file (Word/Latex/Zip) used for generating the PDF.
• 3) all figure and table images in TIFF and JPEG format only, RGB color mode, minimum resolution required: Line Art 900 dpi, Combination (Line Art + Halftone) 600 dpi, Halftone 300 dpi.
  Tables should be inserted into the manuscript in source form (doc, latex).

Step 7: Specify conflict of interest statement and agree to Frontiers copyrights.
Step 8: Preview your submission and submit all. You can save and resume your submission at any step. If you do so, you will find your article in: My Frontiers => For Authors => In Preparation Articles.

For any question, please do not hesitate to contact the Frontiers Editorial Office at:
editorial.office@frontiersin.org

For Commentaries, Book Reviews and Technology Reports:
Directly send your manuscript (.doc, .pdf and high resolution figures) to editorial.office@frontiersin.org.

Please view the table below for a summary on currently accepted article types and general manuscript style guidelines.

	Submitted through	Peer Review	Manuscript length	Number of figures/tables	Author Fees	Submitted to PubMed for Indexing
Tier 1 Frontiers Speciality Journals
Original Research Article	Frontiers Submission System	Yes	Encouraged: up to 12 PDF pages	Up to 15	Yes	Yes
Hypothesis and Theory Articles	Frontiers Submission System	Yes	Encouraged: up to 12 PDF pages	Up to 15	Yes	Yes
Perspective Articles	Frontiers Submission System	Yes	5 PDF pages	Up to 3	Yes	Yes
Methods Article	Frontiers Submission System	Yes	Encouraged: up to 12 PDF pages	Up to 15	Yes	Yes
Review Article	Frontiers Submission System	Yes	Encouraged: up to 12 PDF pages	Up to 20	Yes	Yes
Frontiers Commentary	editorial.office@frontiersin.org	Yes	1 PDF page	Up to 1	No	Yes
General Commentary	editorial.office@frontiersin.org	Yes	1 PDF page	Up to 1	No	Yes
Book Review	editorial.office@frontiersin.org	No	5 PDF pages	Up to 3	No	Yes
Opinion Article	editorial.office@frontiersin.org	No	2 PDF pages	Up to 1	No	No
Technology Report	editorial.office@frontiersin.org	No	½-1 PDF page	Up to 1	No	No
Tier 2 Frontiers in Neuroscience
Focused Review	Frontiers Submission System	Yes	5 PDF pages	Up to 5	No	Yes
Focused Commentary	editorial.office@frontiersin.org	Yes	1 PDF page	Up to 1	No	Yes

General Style Guidelines for your Manuscript (Tier 1)

Manuscript Length
For Original Research, Hypothesis and Theory, Methods and Review Articles: Frontiers encourages a standard article length of 12 pages as in the final PDF version. Your manuscript should contain no more than 12,000 words, including tables figures, and references. Please note that this number has to be drastically lowered if you include figures in your manuscript.

For Perspectives Articles and Book Reviews: Frontiers encourages a standard article length of 5 pages as in the final PDF version. Your manuscript should contain maximally 4,000 to 5,000 words, including tables figures, and references. Please note that this number has to be lowered drastically if you include figures in your manuscript.

For Opinion Articles: Frontiers encourages a standard article length of 2 pages as in the final PDF version. Your manuscript should contain maximally 1,500 to 2,000 words, including 1 table or figure, and references. Please note that this number has to be lowered drastically if you include a figure in your manuscript.

For Commentaries and Technology Reports: Frontiers limits a standard article length of 1 page as in the final PDF version. Your manuscript should contain no more than 1,000 words, including references and one table or figure at the maximum. Please note that this number has to be lowered drastically if you include a figure in your manuscript.

Title
Title is centered in 16 point bold Times New Roman font at the top of page. Except for special names (eg., GABAergic), capitalize only the first letter of the title.

Authors and Affiliations
All names are listed together with comas. Affiliations should be keyed to the author’s name with superscript numbers. Affiliations are listed below, without detailed address information such as city zip codes or street names.
Corresponding Author should be marked with an asterisk. Please provide in a separate paragraph the exact contact address (this time including street name and city zip code) and email of the corresponding author. Please see the following example:

Correspondence:

Dr. Max Maximus

International Institute of Neuroscience

Department of Physiology

Laboratory of Sensory Integration

Cajal Street 2460,

New York, NY, 59066, USA

maximus@gmail.com

If one of the authors has a change of address, then use a superscript symbol and list the Present Address here.

Running Title
A maximum of 5 words.
For Commentaries and Technology Reports: no Running Title is required.

Headings and sub-headings
Except for special names (eg. GABAergic), capitalize only the first letter of headings and subheadings.

• Abstract, Keywords, Acknowledgements, Disclosure/Conflict-of-Interest Statement and References are mandatory, unnumbered, 12 point bold Times New Roman
• Headings and subheadings are numbered, Times New Roman, 12, bold. Note that numbering always ends with a period (e.g. 1. Introduction or 2.1. NMDARs in the amygdala or 3.2. Sleep-dependent IEG expression). You may insert up to 4 heading levels into your manuscript (not more than for example: 3.2.2.1. REM).
• For Original Research Articles, the following sections are mandatory: Introduction, Material and Methods, Results and Discussion, numbered, may contain subheadings (also numbered), 12 point bold Times New Roman. Note that Numbering always ends with a period (e.g. 2.1. Animals or 3.2. Sleep-dependent IEG expression). You may insert up to 4 heading levels into your manuscript (not more than for example: 3.2.2.1. REM).

Abstract
The primary goal of the Abstract should be to make the general significance and conceptual advance of the work clearly accessible to a broad readership. References should not be cited in the Abstract. The text of the abstract section should be in normal body text.

For Original Research, Hypothesis and Theory, Methods and Review Articles, the abstract is a single paragraph containing no more than 250 words.

For Perspectives Articles, the abstract is a single paragraph containing no more than 150 words.

Please note that Opinion Articles, Commentaries, Technology Reports and Book Reviews do not contain an abstract.


Keywords
For Original Research, Hypothesis and Theory, Methods and Review Articles: a maximum of 8 keywords.
For Perspectives Articles: a maximum of 5 keywords.
For Opinion Articles, Commentaries and Technology Reports and Book Reviews: no keywords.

Text
The body text is in 12 point normal Times New Roman. New paragraphs will be separated with a single empty line. The entire document should be single-spaced. Your manuscript should be written using either LaTeX or MS-Word (DOC).

Abbreviations
Non-standard abbreviations should be defined when first used in the text.

Equations
Equations can be left as the image output of the equation editor in the text.

Figure and Table Legends
Figures and Tables should be inserted into the text where they are mentioned.

Figure and table legends are the same as body text (12 point normal Times New Roman, single spaced). Legends should be preceded by a label, for example "Figure 1." or "Table 4.". Figure legends should be placed immediately after the figure. Please use only a single paragraph for the legend. Figure panels are refereed to by bold capital letters in brackets: (A), (B), (C), (D), etc...

Sections
Your manuscript is organized by headings and subheadings.
For Original Research Articles, the following sections are mandatory:

• 1. Introduction
  Succinct, with no subheadings.
• 2. Material and Methods
  This section may be divided by subheadings. This section should contain sufficient detail so that when read in conjunction with cited references, all procedures can be repeated.
• 3. Results
  This section may be divided by subheadings. Footnotes should not be used and have to be transferred to the text.
  Gene symbols should be italicized; protein products are not italicized.
• 4. Discussion
  This section may be divided by subheadings.
  Discussions should cover the key findings of the study, discuss any prior art related to the field in order to place the novelty of the discovery in the appropriate context, discuss their potential short-comings & limitations on their interpretations, discuss their integration into the current understanding of the problem and how this advances the current views, speculate on the future direction of the research and freely postulate theories that could be tested in the future.

Authorization for the Use of Experimental Animals or Human Subjects
All experiments on live vertebrates or higher invertebrates must be performed in accordance with relevant institutional and national guidelines and regulations. In the manuscript, authors must identify the committee approving the experiments and must confirm that all experiments conform to the relevant regulatory standards. For manuscripts reporting experiments on human subjects, authors must identify the committee approving the experiments and must also include a statement confirming that informed consent was obtained from all subjects. In Original Research Articles, these statements should appear in the Materials and Methods section.

Conflict of Interest Statement
All relationships financial, commercial or otherwise that might be perceived by the scientific community as representing a potential conflict of interest must be described.
If no such relationship exists, authors will be asked to agree to declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Acknowledgments
The Acknowledgements header is unnumbered (Times New Roman, 12pt, bold). Short text to acknowledge the contributions of specific colleagues, institutions, or agencies that aided the efforts of the authors, to be published as an acknowledgment. A statement about the principal source of funding is encouraged, including grant numbers if appropriate.

Supplemental Material
Frontiers Journals do not support pushing important results and information into supplementary sections. All information in form of additional text, graphs, tables shall be included into the original text.
However, supplemental material that cannot be included in the article because it is too large or the current format does not permit it, such as movies, raw data traces, power point presentations, etc can be uploaded during the submissions procedure and will be displayed along with the published article.

References
All citations in the text, figures or tables must be in the reference list and vice-versa. Please make sure that the references are accurate.
References should be called according to the last name of the first author, followed by the year. Endnotes or other bibliographic software programs should be configured to the Elsevier family of journals, including Neuroscience.
The references include only articles that are published or in press. Unpublished data, submitted manuscripts, or personal communications should be cited within the text only. Personal communications should be documented by a letter of permission.
Please use the following style for references:

Article in a periodical:
Sondheimer, N., and Lindquist, S. (2000). Rnq1: an epigenetic modifier of protein function in yeast. Mol. Cell 5, 163-172.

Article in a book:
Sorenson, P.W., and Caprio, J.C. (1998). Chemoreception. In The Physiology of Fishes, D.H. Evans, ed. (Boca Raton, FL: CRC Press), pp. 375-405.

An entire book:
Cowan, W.M., Jessell, T.M., and Zipursky, S.L. (1997). Molecular and Cellular Approaches to Neural Development (New York: Oxford University Press).

General Style Guidelines for Images and Figures

Figures should be embedded as images in the manuscript where they are mentioned. Please check that each table and figure is mentioned in the text and in numerical order. Please insure that permission has been obtained for use of copyrighted material from other sources (including the Web).
Please note that is obligatory to follow figure instructions. Figures which are not according to the guidelines will cause substantial delay during the production process.
High-resolution images MUST also be submitted separately in the formats described below. Images should be flushed left. There should be no text on the same horizontal level as the image. An empty line should be left before and after the image. The resolution of images embedded in the .DOC and .PDF files should be sufficient so that all figures are legible.

Number of Images / Tables

For Original Research, Hypothesis and Theory, Methods and Review Articles: up to 15 figures or tables are permitted.
For Perspectives Articles and Book Reviews: up to 3 figures or tables are permitted.
For Opinion Articles, Commentaries and Technology Reports: Frontiers accepts 1 figure or 1 table at the maximum.

Image Size
Figure images should be prepared with the PDF/journal layout in mind, with a width that corresponds to either 1 column, 2 columns or 3 columns.
For Original Research, Hypothesis and Theory, Methods, Review and Perspectives Articles, image width shall be 85 mm (1 column) or 180 mm (2 columns).
For Opinion Articles, Commentaries, Technology Reports and Book Reviews, image width shall be 55 mm (1 column), 120 mm (2 columns), or 180 mm (3 columns).

Text within the Figure
Text in Figures and Tables should be in Arial font and no smaller than 8 points when reduced to one of the two formats mentioned above. Figure panels are lettered by bold capital letters: A, B, C, D, etc.

Format
The following formats are accepted:

• EPS (.eps)
• TIFF (.tif)
• JPEG (.jpg)

Color Image Mode
Please submit your images in the color mode RGB.

Resolution Requirements
It is obligatory to upload separately high resolution images in the submission procedure.
For black and white line art the minimum resolution should be 900 dpi. For halftone figures (photographs), the resolution should be a minimum of 300 dpi. For any type of graph or drawing in grayscale or combinations between line art and halftone, the resolution of your file should be a minimum of 600 dpi.
These resolutions are required for figure size specified previously. If your figure is smaller, then the resolution has to be higher. Test the resolution of your figure on a computer screen at 400% enlargement.

Please see the table below exemplifying the image specifications.


These image specifications were modified from PubMed Central and are fully compatible with submitting your article to PubMed Central.

Legibility

Figures must be legible. Please check the following:
The smallest visible text is no less than 8 points in height, when viewed at actual size.
Example: THIS IS 8 PT TEXT.
Solid lines are not broken up.
Image areas are not pixilated or stair stepped.
Text is legible and of high quality.
Any lines in the graphic are no smaller than 2 points width.
Figure File Naming
Please name figure files by first author and number of figure, e.g., Maximus_Figure_1.tif, Maximus_Figure_2.tif, etc…

General Style Guidelines for Tables

Tables should be embedded into the manuscript where they are mentioned. If you use a word processor, build your table in word. If you use a LatTex processor, build your table in Latex. If you use any other format save your table as an image and follow the image and figure instructions. Tables should be flushed left. An empty line should be left before and after the table. The font size embedded in the .DOC and .PDF files should be sufficient to be legible.

Table Size
Table images should be prepared with the PDF/journal layout in mind, with a width that corresponds to either 1 column or 2 columns if they are displayed vertically, or any length up to 22 cm if they are displayed horizontally.

Table File Naming if Saved as Image
Please name table files by first author and number of table, e.g., Maximus_Table_1.tif, Maximus_ Table_2.tif, etc.

What are the next steps?

Review of your manuscript
Your manuscript will be reviewed by 2 reviewers. You will receive a notification as soon as the reviewers have submitted their Independent Review Reports and the Interactive Review Forum is activated. You will then be able to interact with the reviewers in the Interactive Review Forum and also re-submit a new manuscript if necessary.
Finally, upon finalization of the review an editorial decision will be taken and you will be notified immediately.

Production of your article
If your manuscript is accepted by the Associate Editor, then the production process starts immediately. For any question, please do not hesitate to contact the Frontiers Production Office at: production.office@frontiersin.org
Proofs are sent to the corresponding author for checking and correction. At this step, the typesetter might ask you for higher quality figures if needed. In order to prevent this delay in the production process, please make sure that your images, figures and tables are according to the specified guidelines.

Publication of your article
Your article will be published online in PDF and HTML formats in the Frontiers Journal website. Files are also submitted to PubMed Central and will be online there some weeks after. From day of acceptance onwards, you can track the impact of your article on the community. Check out the Frontiers Article Analytics button next on your abstract page.