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Research Topics

Displaying 1 - 20 out of 85 Research Topics

G protein-coupled receptors: neuromodulation and diseases

Topic Editors:
Hansen Wang, University of Toronto, Canada

G protein-coupled receptors (GPCRs) are a superfamily of seven transmembrane receptors that recognize a diverse array of extracellular stimuli and widely exist in the...

Deadline for full article submission: 31 Dec 2016

Submission Open.

Cannabinoids and vanilloids as emerging therapeutical targets for neuropsychiatric disorders – basic and clinical evidence

Topic Editors:
Vanessa C. Abilio, Universidade Federal de Sao Paulo, Brazil
José Alexandre Crippa, University of São Paulo, Brazil
Regina H. Silva, Federal University of Rio Grande do Norte, Brazil

Neuropsychiatric disorders are severely debilitating. They can bring a great deal of suffering to the patients and their families/ health caregivers. In addition, the...

Deadline for abstract submission: 30 Sep 2015

Deadline for full article submission: 31 Mar 2016

Submission Open.

Hepatic Fibrogenesis

Topic Editors:
Geetha Samak, DVS College of Arts and Science, India
Sandeep B. Subramanya, RAK Medical and Health Sciences University, United Arab Emirates
Damodaran M. VASUDEVAN, Amrita Institute of Medical Sciences, India
Kotambail Venkatesha Udupa, University College Dublin and St Vincent's University Hospital, Ireland

Liver cirrhosis is increasingly becoming the major cause of global health burden. It originates through a dynamic process of liver fibrogenesis and fibrosis. Excessive...

Deadline for abstract submission: 16 Jun 2015

Deadline for full article submission: 15 Dec 2015

Submission Open.

Structural needs for multi-target compounds in treatment of neurodegenerative disorders

Topic Editors:
Magdalena Majekova, Institute of Experimental Pharmacology & Toxicology, Slovak Academy of Sciences, Slovakia
Katarina Nikolic, Faculty of Pharmacy, University of Belgrade, Serbia
Maria D. Carreiras, Faculty of Pharmacy, University of Lisbon, Portugal
Marian VALKO, Slovak Technical University, Faculty of Chemical and Food Technology, Slovakia
Stefania Butini, European Research Centre for Drug Discovery and Development (NatSynDrugs), University of Siena, Italy

The multi-factorial character of numerous chronic diseases has been commonly accepted as the basis for understanding mechanisms of disease processes and also for the...

Deadline for abstract submission: 31 Aug 2014

Deadline for full article submission: 30 Nov 2014

Extended deadline for full article submission: 31 Aug 2015

Submission Open.

Cyclic and linear polysiloxanes (silicones) in pharmacy, medicine, personal care products, food, environment – safety or risk?

Topic Editors:
Krystyna Mojsiewicz-Pienkowska, Faculty of Pharmacy with Subfaculty of Laboratory Medicine, Medical University of Gdansk, Poland
Marzena Jamrógiewicz, Medical University of Gdansk, Faculty of Pharmacy with Subfaculty of Laboratory Medicine, Poland

Cyclic and linear polysiloxanes (silicones) belong to the organosilicon compounds. Because of their unique properties, polysiloxanes could be found almost in all areas of...

Deadline for abstract submission: 31 May 2015

Deadline for full article submission: 31 Aug 2015

Submission Open.

Matricellular receptors as potential targets in anti-cancer therapeutic strategies

Topic Editors:
Hervé Emonard, Centre National de la Recherche Scientifique (CNRS), France
Stéphane Dedieu, CNRS UMR 7369 MEDYC and Reims University, France
Laurent DUCA, University of Reims Champagne-Ardenne, France

The invasive character of a primary cancer is greatly dependent on numerous interactions between tumor cells and their extracellular surroundings. Matricellular receptors...

Deadline for abstract submission: 01 Mar 2015

Deadline for full article submission: 15 Aug 2015

Submission Open.

The next generation of deafness therapies targeting the inner ear

Topic Editors:
Hiroshi Hibino, Niigata University, Japan

Numerous people are suffering from inner-ear disorders throughout the world, providing severe social and financial impacts. Classical drugs such as steroids and vitamins...

Deadline for abstract submission: 31 May 2014

Deadline for full article submission: 30 Jul 2014

Extended deadline for full article submission: 31 Jul 2015

Submission Open.

Herbal Hepatotoxicity: New Advances, Scientific Mechanisms and Rational Usage

Topic Editors:
Jia-bo Wang, 302 Military Hospital of China, China
Xiaohui Fan, Zhejiang University, China
Luyong Zhang, China Pharmaceutical University, China
Xiao-he Xiao, 302 Military Hospital of China, China

Herbal hepatotoxicity, an unresolved critical issue which impacts clinical safety of herbal remedies worldwide, has been recognized for many years, but new herbal...

Deadline for abstract submission: 31 Jan 2014

Deadline for full article submission: 30 Nov 2014

Extended deadline for full article submission: 19 Jul 2015

Submission Open.

Application of spray drying technology to enhance performance of both small and large drug molecules

Topic Editors:
AMAL A. ELKORDY, university of Sunderland, United Kingdom

Spray drying as a technique is very efficient and beneficial as it converts the contents of solutions/suspensions into dry powder forms in one step. This makes spray...

Deadline for abstract submission: 25 Sep 2014

Deadline for full article submission: 04 Jul 2015

Submission Open.

Pharmacogenetics and Pharmacogenomics in Autoimmune and Autoinflammatory Diseases

Topic Editors:
Vita Dolzan, University of Ljubljana, Faculty of Medicine, Slovenia
Blaz Rozman, Faculty of Medicine Ljubljana, Slovenia

Autoimmune diseases are chronic, debilitating illnesses with an estimated prevalence of around 3% in the human population. However the incidence can be higher in families...

Deadline for abstract submission: 01 Mar 2015

Deadline for full article submission: 30 Jun 2015

Submission Open.

Serotonin and memory

Topic Editors:
Alfredo Meneses, Center for Research and Advanced Studies, Mexico. Mentor: Carlos Gitler, Weizman Institute, Mexico
Antonella Gasbarri, University of l'Aquila, Italy

The study of 5-hydroxytryptamine (5-HT) systems has benefited from the identification, classification and cloning of multiple 5-HT receptors (5-HT1 to 5-HT7). Increasing...

Deadline for abstract submission: 19 Dec 2014

Deadline for full article submission: 30 Jun 2015

Submission Open.

Computational and Experimental Approaches in Multi-target Pharmacology

Topic Editors:
Thomas J. Anastasio, University of Illinois at Urbana-Champaign, USA

Diseases having multifactorial etiologies include cancer and cardiovascular disease, Alzheimer and Parkinson disease, diabetes and obesity, and depression and...

Deadline for abstract submission: 19 Jan 2015

Deadline for full article submission: 19 Jun 2015

Submission Open.

Orphan GPCRs as emerging drug targets

Topic Editors:
Ye Fang, Corning Incorporated, USA
Terry Kenakin, University of North Carolina Chapel Hill, USA
Changlu Liu, Janssen Research & Development, LLC, USA

G protein coupled-receptors (GPCRs) have been proven to be the most successful class of druggable targets in the human genome. It is estimated that 30 to 50% of all...

Deadline for abstract submission: 31 Aug 2014

Deadline for full article submission: 28 Nov 2014

Extended deadline for full article submission: 15 Jun 2015

Submission Open.

In silico modeling of brain receptors for antidepressants, psychostimulants and other CNS-active drugs

Topic Editors:
Christopher Surratt, Duquesne University, USA
Jeffry D. Madura, Duquesne University, USA

Brain receptors for drug classes including antidepressants, antipsychotics, psychostimulants, opiates and anticonvulsants are typically embedded in the lipid bilayer of...

Deadline for abstract submission: 09 Jan 2015

Deadline for full article submission: 06 Mar 2015

Extended deadline for full article submission: 01 Jun 2015

Submission Open.

Apolipoprotein AI and high-density lipoproteins in the prevention and treatment of disease

Topic Editors:
Norman E. Miller, Magdalen College, Oxford, UK, United Kingdom
John M. Chapman, INSERM, France
Gwendalyn J. Randolph, Washington University School of Medicine, United States
Gerald F. Watts, UWA, Australia

High-density lipoproteins (HDLs) and their lipid and protein components, of which apolipoprotein AI (apo AI) is the principal protein by weight, continue to be the focus...

Deadline for abstract submission: 15 Apr 2015

Deadline for full article submission: 31 May 2015

Submission Open.

In Vivo Imaging in Pharmacological Research

Topic Editors:
Nicolau Beckmann, Novartis Institutes for BioMedical Research, Switzerland
Albert D Windhorst, VU University Medical Center, Netherlands
Igor A. Kaltashov, University of Massachusetts - Amherst, USA

The discovery and development of a biological active molecule with therapeutic properties is an ever increasing complex task, highly unpredictable at the early stages and...

Deadline for abstract submission: 01 Dec 2014

Deadline for full article submission: 31 May 2015

Submission Open.

Frontiers in the pharmacological manipulation of intracellular cAMP levels

Topic Editors:
George S. Baillie, Glasgow University, United Kingdom
Frank Christian, University of Glasgow, United Kingdom
Apostolos Zarros, University of Glasgow, United Kingdom

Cyclic adenosine monophosphate (cAMP) is a second messenger of paramount biological importance, involved in the regulation of a significant number of cellular functions...

Deadline for abstract submission: 30 Jan 2015

Deadline for full article submission: 29 May 2015

Submission Open.

The Development, Marketing and Clinical Use of Enantiomers: Substantive Improvement in Patient Care or a Cynical Ploy for Manufacturer Profit?

Topic Editors:
David F. Lehmann, SUNY Upstate Medical University/UUH, USA
Sarabeth Wojnowicz, Upstate Medical University, USA

Medications that exist as racemic mixtures contain an equal mix of stereoisomers that have the same physical and chemical properties. These isomers can then be separated...

Deadline for abstract submission: 14 Nov 2014

Deadline for full article submission: 15 May 2015

Submission Open.

Memory deficits & brain alterations

Topic Editors:
Alfredo Meneses, Center for Research and Advanced Studies, Mexico. Mentor: Carlos Gitler, Weizman Institute, Mexico
Antonella Gasbarri, University of l'Aquila, Italy

Dysfunctional memory occurs in several neuropsychiatric disorders, including schizophrenia, stroke, post-traumatic stress disorder. Certainly, Alzheimer´s disease (AD) is...

Deadline for abstract submission: 14 Nov 2014

Deadline for full article submission: 15 May 2015

Submission Open.

Recent advances in voltage-gated sodium channels, their pharmacology and related diseases

Topic Editors:
Mohamed Chahine, Laval University, Canada
Jean-François Desaphy, University of Bari "Aldo Moro", Italy

It is our pleasure to co-edit a Research Topic on voltage-gated sodium channels pharmacology and related diseases. We are in a process to inviting submissions of novel...

Deadline for abstract submission: 01 Nov 2014

Deadline for full article submission: 01 Apr 2015

Extended deadline for full article submission: 01 May 2015

Submission Open.

Displaying 1 - 20 out of 85 Research Topics

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