Fabrication of Multi-Electrode Array with Iridium Oxide-Electrodeposited on Indium-Tin Oxides Nanowires
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1
Electronics and Telecommunications Research Institute, Republic of Korea
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2
Wonkwang University, Department of Physiology, Republic of Korea
Multi-electrode arrays (MEAs) were fabricated with electrodes consisting of iridium oxide (IrOx) electrodeposited on indium-tin oxide nanowires (ITO NWs) grown on ITO electrode using RF magnetron sputtering technique. The elemental mapping analysis of the cross-sectional structure of the IrOx/ITO NW hybrid electrodes revealed that the IrOx had been uniformly deposited on the surface of the surface of ITO nanowire.
The charge injection limit of the IrOx/ITO NW MEA was estimated to be 1.9 mC cm-2 by measuring the voltage transient, and this value is sufficiently greater than the neural damage threshold (ca. 1 mC cm-2). The efficacy of the improvement in the charge injection limit of the IrOx/ITO NW MEA was evaluated with rat hippocampal slices. The IrOx/ITO NW electrodes exhibited a steeper increase in the negative peak amplitude of the field excitatory postsynaptic potentials, even with an electrical stimulation of a lower amplitude, prolonged negative fEPSPs wave after peak response, all of which strongly indicate an improved charge injection for the IrOx/ITO NW MEA.
Acknowledgements
This work was supported by ETRI (18ZH1500).
Keywords:
Indium-tin oxide nanowire,
electrodeposited iridium oxide,
multielectrode array,
Electrical Stimulation,
Charge injection limit,
Field excitatory postsynaptic potential,
Long-Term Potentiation
Conference:
MEA Meeting 2018 | 11th International Meeting on Substrate Integrated Microelectrode Arrays, Reutlingen, Germany, 4 Jul - 6 Jul, 2018.
Presentation Type:
Poster Presentation
Topic:
Microelectrode Array Technology
Citation:
KIM
Y,
JUNG
S,
Koo
H and
Kim
M
(2019). Fabrication of Multi-Electrode Array with Iridium Oxide-Electrodeposited on Indium-Tin Oxides Nanowires.
Conference Abstract:
MEA Meeting 2018 | 11th International Meeting on Substrate Integrated Microelectrode Arrays.
doi: 10.3389/conf.fncel.2018.38.00107
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Received:
19 Mar 2018;
Published Online:
17 Jan 2019.
*
Correspondence:
Dr. SNAG-DON JUNG, Electronics and Telecommunications Research Institute, Daejeon, 34129, Republic of Korea, jungpol@etri.re.kr