Theta and Alpha EEG Rhythms and BOLD Responses Associated with Working Memory Tasks
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1
University of Campinas – UNICAMP, Neuroimaging Laboratory, School of Medical Sciences, Brazil
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2
University of Campinas , Neurophysics Group, Gleb Wataghin Physics Institute, Brazil
The correlation between EEG rhythms and BOLD signal in working memory studies is still controversial. We evaluated working memory in normal controls and patients with mesial temporal lobe epilepsy (MTLE) associated with left hippocampal atrophy (HA) by means of EEG and functional Magnetic Resonance Imaging (fMRI).
EEG data indicated the presence of theta oscillations in the frontal region and alpha oscillations in the parieto-occipital region, in both groups. Correlations were established among these rhythms and both, positive and negative BOLD responses, but in different regions.
Although both groups have presented similar performance for memory tests, there were discrepancies between them in terms of the cortical structures involved in the memory task during EEG/fMRI examination. In the control group, it was found predominance of activation at the left hemisphere whereas for the patient group activation was equally distributed over both hemispheres, probably due to damage in the left mesial temporal lobe structures. Such a finding is suggestive of the neuroplasticity phenomenon by which additional cortical areas would be recruited to compensate the brain structures affected by atrophy.
Conference:
The 20th Annual Rotman Research Institute Conference, The frontal lobes, Toronto, Canada, 22 Mar - 26 Mar, 2010.
Presentation Type:
Poster Presentation
Topic:
Cognitive Neuroscience
Citation:
Alessio
A,
Bilevicius
E,
Cendes
F,
Covolan
R,
Damasceno
B,
Ozelo
H,
Pedro
T,
Pereira
F and
Sercheli
M
(2010). Theta and Alpha EEG Rhythms and BOLD Responses Associated with Working Memory Tasks.
Conference Abstract:
The 20th Annual Rotman Research Institute Conference, The frontal lobes.
doi: 10.3389/conf.fnins.2010.14.00122
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Received:
30 Jun 2010;
Published Online:
30 Jun 2010.
*
Correspondence:
R J M Covolan, University of Campinas, Neurophysics Group, Gleb Wataghin Physics Institute, Campinas, Brazil, covolan@ifi.unicamp.br