The effect of Som Jawa (Talinum triangulare) on BALB/c mice swimming time
-
1
Diponegoro University, Indonesia
Background
Som Jawa (Talinum triangulare) is a plant commonly found in Central Java that has been believed has potency as Korean Ginseng. The aim of the study is to investigate the effect of Som Jawa on mice swimming time as a parameter of physical endurance.
Method
Study design was a pre-post test parallel groups design. Samples were male, 3 months old BALB/c mice (n=27). Mice were randomly allocated into 3 groups: Group I was given 18.2 mg of Som Jawa root extract in 0.5 cc aquadest, group II was given 0.5 cc supplement drink and Group III was given 0.5 cc aquadest. All treatments were given through gastric instillation once a day. Measured parameter is the length of swimming time. Swimming time were collected at day 0 (pre) and day 15 (post). Delta swimming time was calculated by substracting post – pre swimming time. The difference of swimming time of treatment group was analyzed using-Kruskall-Wallis and Mann-Whitney test.
Results
Delta swimming time in Group I was 41.9±35.36 second, group II was 27.1±39.17 second and group III was 1.3±5.00 second. Group I was not significantly higher than group II (p=0.4), group I was significantly higher than group III (p=0.003). The difference between group II and group III was not significant (p=0.2).
Conclusion
Som Jawa (Talinum triangulare) administration increased swimming time of the mice.
Keywords:
Javanese ginseng,
Swimming time,
ginseng,
Mice,
Endurance
Conference:
International Conference on Drug Discovery and Translational Medicine 2018 (ICDDTM '18)
“Seizing Opportunities and Addressing Challenges of Precision Medicine”, Putrajaya, Malaysia, 3 Dec - 5 Feb, 2019.
Presentation Type:
Oral Presentation
Topic:
Neurodegenerative diseases
Citation:
Hardian
H,
Purwoko
Y,
Gumay
AR,
Muniroh
M,
Indraswari
DA and
Apsari
AA
(2019). The effect of Som Jawa (Talinum triangulare) on BALB/c mice swimming time.
Front. Pharmacol.
Conference Abstract:
International Conference on Drug Discovery and Translational Medicine 2018 (ICDDTM '18)
“Seizing Opportunities and Addressing Challenges of Precision Medicine”.
doi: 10.3389/conf.fphar.2019.63.00002
Copyright:
The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers.
They are made available through the Frontiers publishing platform as a service to conference organizers and presenters.
The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated.
Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed.
For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions.
Received:
29 Nov 2018;
Published Online:
17 Jan 2019.
*
Correspondence:
Dr. Hardian Hardian, Diponegoro University, Semarang, Indonesia, dokterhardian@gmail.com