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Role of red fruit (pandanus conoideus) towards photoaging inhibition in mice skin

Renni Yuniati1*, Sylvia C. Sugianto2, Saekhol Bakri3, Dwi Retnoningrum4 and Farmaditya Mundhofir5
  • 1 Diponegoro University, Department of Dermatology and Venereology, Indonesia
  • 2 Diponegoro University, Indonesia
  • 3 Diponegoro University, Department of Public Health, Indonesia
  • 4 Diponegoro University, Department of Clinical Pathology, Indonesia
  • 5 Diponegoro University, Department of Histology, Indonesia

Background Early aging is caused by sunlight exposure and can be prevented by antioxidant administration. Lately, people tend to use natural ingredients that contain antioxidants. Red fruit from Papua contains a lot of antioxidants and can be used as one of the alternatives to prevent early aging. This study aimed to know the role of red fruit towards photoaging inhibition, which was assessed from total number of type I procollagen in mice skin. Methods This was an animal experimental study, mice was used as the model animal and was divided into 3 groups. Group 1 was control group, group 2 was exposed with ultraviolet ray from artificial source, group 3 was exposed with ultraviolet ray and recieved red fruit orally. Biopsy of the skin was done after treatment, checked using immunohistochemistry with staining of type I procollagen and then evaluated using computer program. Result This study showed an increased expression of type I procollagen in group 3 compared with group 2. Conclusion Red fruit can be used to prevent photoaging.

References

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Keywords: Photoaging, red fruit, Pandanus conoideus, Type I procollagen, Antiaging

Conference: International Conference on Drug Discovery and Translational Medicine 2018 (ICDDTM '18) “Seizing Opportunities and Addressing Challenges of Precision Medicine”, Putrajaya, Malaysia, 3 Dec - 5 Feb, 2019.

Presentation Type: Oral Presentation

Topic: Miscellaneous

Citation: Yuniati R, Sugianto SC, Bakri S, Retnoningrum D and Mundhofir F (2019). Role of red fruit (pandanus conoideus) towards photoaging inhibition in mice skin. Front. Pharmacol. Conference Abstract: International Conference on Drug Discovery and Translational Medicine 2018 (ICDDTM '18) “Seizing Opportunities and Addressing Challenges of Precision Medicine”. doi: 10.3389/conf.fphar.2019.63.00016

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Received: 14 Nov 2018; Published Online: 17 Jan 2019.

* Correspondence: MD, PhD. Renni Yuniati, Diponegoro University, Department of Dermatology and Venereology, Semarang, Central Java, 50275, Indonesia, renniyuniati@yahoo.com