Osteoconductivity and protein adsorbability of surface modified titanium implants using hydroprocessing
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1
Nagoya University, EcoTopia Science Institute, Japan
Surface hydrophilicity is considered to have a strong influence on the biological reactions of bone-substituting materials. However, the influence of a hydrophilic or hydrophobic surface on the osteoconductivity is not completely clear. In this study, we produced super-hydrophilic and hydrophobic surface on Ti and Ti alloys using a hydrothermal treatment at 180 oC for 180 min. in the distilled water. Hydrothermal treated samples were stored in x5 PBS(-). This maintained less than 10 (deg.) in an apparent water contact angle of them. The osteoconductivity of the surface treated samples with several water contact angle was evaluated with a protein (albumin fibronectin, and decorin) adsorption and in vivo testing. The water contact angle of around 65 deg. minimized the hard tissue formation and protein adsorption on the samples. And more hydrophilic and hydrophobic surfaces had higher hard tissue formation rate and more protein adsorption with decreasing or increasing the water contact angle. That is to say that the surface properties, especially water contact angle, strongly affected on the osteoconductivity.
Keywords:
in vivo,
Implant,
Surface modification,
bioactive interface
Conference:
10th World Biomaterials Congress, Montréal, Canada, 17 May - 22 May, 2016.
Presentation Type:
Poster
Topic:
Surface and interfacial characterization
Citation:
Kuroda
K and
Okido
M
(2016). Osteoconductivity and protein adsorbability of surface modified titanium implants using hydroprocessing.
Front. Bioeng. Biotechnol.
Conference Abstract:
10th World Biomaterials Congress.
doi: 10.3389/conf.FBIOE.2016.01.01871
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Received:
27 Mar 2016;
Published Online:
30 Mar 2016.
*
Correspondence:
Dr. Masazumi Okido, Nagoya University, EcoTopia Science Institute, Nagoya, Japan, okido@numse.nagoya-u.ac.jp