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Prevent biofilm formation using TiO2 nanotubes on the Ti-30Ta alloy for biomedical application. abstract created on Wednesday September 30, 2015

Patricia Capellato1, Ana Paula R. Alves Claro2 and Cecilia A De C Zavaglia1
  • 1 Unicamp, Department of Mechanical Engineering, Brazil
  • 2 Unesp, Department of Materials and Technology, Brazil

The nanotubes of TiO2 have been shown to play important rules on biofilme formatin. Infection is a  problem in biomedical field that leading to implant failure.In this study, the self-ordered formation of nanotubular oxide layers on Ti–30Ta was investigated in order to reducing infection.The anodization process was realized in an electrolyte solution containing 0.2M NH4F at 30V for 6 hours]. The nanotube layer was annealed in an oxygen ambient furnace at  530 ºC (5º C/min) for 1 hour.

The Ti-30Ta alloy surface were investigated using  scanning electron microscopy (SEM) and and X-ray diffractometer (XRD). Staphylococcus aureaus and candida albicans  were selected to investigate the  bacterial adhesion and biofilm formation.

The results indicated that the bacterial response was highly influenced by anodization process on Ti-30Ta alloy with TiO2 nanotube fabrication.

Fapesp; Cnpq; Unesp; Unicamp; INct

References:
[1] ALLAM, N. K.; FENG, X. J.; GRIMES, C. A. Self-Assembled Fabrication of Vertically Oriented Ta2O5 Nanotube Arrays, and Membranes Thereof, by One-Step Tantalum Anodization. Chemistry of Materials, v. 20, n. 20, p. 6477-6481, 2008.
[2] CAPELLATO, P. et al. Fibroblast functionality on novel Ti30Ta nanotube array. Materials Science and Engineering: C , v. 32, n. 7, p. 2060- 2067,2012.
[3] SMITH, B. S. et al. Dermal fibroblast and epidermal keratinocyte functionality on titania nanotube arrays. Acta Biomaterialia, v. 7, n. 6, p. 2686-2696, 2011.

Keywords: Bacteria, Biocompatibility, Surface modification, nanotube

Conference: 10th World Biomaterials Congress, Montréal, Canada, 17 May - 22 May, 2016.

Presentation Type: Poster

Topic: Nanotopography of biomaterials

Citation: Capellato P, Alves Claro AR and Zavaglia C (2016). Prevent biofilm formation using TiO2 nanotubes on the Ti-30Ta alloy for biomedical application. abstract created on Wednesday September 30, 2015. Front. Bioeng. Biotechnol. Conference Abstract: 10th World Biomaterials Congress. doi: 10.3389/conf.FBIOE.2016.01.02954

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Received: 27 Mar 2016; Published Online: 30 Mar 2016.