Event Abstract

Back to Event

The prevalence of wheezing and its relationship with some environmental factors in children aged 6-7 in Yazd

Mojtaba Mirzaei1* and Mohsen Mirzaei2*
  • 1 Tehran University of Medical Sciences and Health Care, Iran
  • 2 Yazd University Of Medical Sciences and Health Care, Iran

Backgrounds: Asthma is an inflammatory disease of conducting airways which affects quality of life of children, also posing a high level of burden on health care system. Avoiding exposure to environmental allergens is a well-known method for control of symptoms of asthma.

Objectives: To measure the prevalence of wheezing among children who were exposed to different environmental factors.

Methods: In this cross sectional study, parents of 2740 children aged 6-7 attending selected schools in Azadshahr, Yazd, received the International Study of Asthma and Allergies in Childhood (ISAAC) written questionnaire. The children were classified according to exposure to cigarette smoking (mother vs. father vs. babysitter) and keeping cats and dogs (in first year of life vs. past 12 months) at home.

Results: Prevalence of wheezing was 10.9 (12.9% among boys and 8.4% among girls) ,and only 3.8% claimed physician assessed asthma diagnosis.
Prevalence of wheezing was significantly increased in those with the history of keeping cats at home for past 12 months.(12.2% vs. 8.5%. p value : 0.03) ,in addition having a smoker mother was associated with increased wheezing.(2.4% vs. 1%. P value: 0.04).
Other associations were not statistically significant.

Conclusion: smoker mother and keeping cats at home in past 12 months were associated with increase of wheezing among children of our study

References

1.Gupta R, Anderson HR, Strachan DP, et al. International trends in admissions and drug sales for asthma. Int J
Tuberc Lung Dis 2006;10:138–45

2.Yangzong Y, Shi Z, Nafstad P, Håheim LL, Luobu O, Bjertness E.The prevalence of childhood asthma in China: a systematic review.BMC Public Health. 2012 Oct 10;

3.Holgate S., Bisgaard H., Bjermer L., Haahtela T., Haughney J., Horne R., McIvor A., Palkonen S., Price D. B., Thomas M., et al. The Brussels Declaration: the need for change in asthma management. Eur. Respir. J. 2008;32:1433–1442

4.Stanford RH, Gilsenan AW, Ziemiecki R, Zhou X, Lincourt WR, Ortega H. Predictors of uncontrolled asthma in adult and pediatric patients: analysis of the Asthma Control Characteristics and Prevalence Survey Studies (ACCESS).
J Asthma. 2010 Apr;47

5.Asher MI, Keil U, Anderson HR, Beasley R, Crane J, Martinez F, Mitchell EA, Pearce N, Sibbald B, Stewart AW, Strachan D, Weiland SK, Williams HC: International Study of Asthma and Allergies in Childhood (ISAAC): Rationale and methods. European Respiratory Journal 1995, 8:483-91.

6.Asher MI, Stewart AW, Mallol J, Montefort S, Lai CK, Aït-Khaled N, Odhiambo J; ISAAC Phase One Study Group. Which population level environmental factors are associated with asthma, rhinoconjunctivitis and eczema? Review of the ecological analyses of ISAAC Phase One.
Respir Res. 2010 Jan 21;11:8.


7.Sistek D, Wickens K, Amstrong R, D'Souza W, Town I, Crane J.
Predictive value of respiratory symptoms and bronchial hyperresponsiveness to diagnose asthma in New Zealand.
Sistek D, Wickens K, Amstrong R, D'Souza W, Town I, Crane J.
Respir Med. 2006 Dec;100(12):2107-11.

8.Grize L, Gassner M, Wüthrich B, Bringolf-Isler B, Takken-Sahli K, Sennhauser FH, Stricker T, Eigenmann PA, Braun-Fahrländer C; Swiss Surveillance Programme on Childhood Allergy and Respiratory symptoms with respect to Air Pollution (SCARPOL) team. Trends in prevalence of asthma, allergic rhinitis and atopic dermatitis in 5-7-year old Swiss children from 1992 to 2001.
Allergy. 2006 May;61(5):556-62.

9.Stipić-Marković A, Pevec B, Pevec MR, Custović A. Prevalence of symptoms of asthma, allergic rhinitis, conjunctivitis and atopic eczema: ISAAC (International Study of Asthma and Allergies in Childhood) in a population of schoolchildren in Zagreb Acta Med Croatica. 2003;57(4):281-5..

10.Radić S, Zivković Z, Erdeljan N, Cerović S, Jocić-Stojanović. influence of environmental tobacco smoke on characteristics of childhood asthma .Srp Arh Celok Lek.. 2009 Mar-Apr;137(3-4):152-9. [Article in Serbian]


11.Burke H, Leonardi-Bee J, Hashim A, Pine-Abata H, Chen Y, Cook DG, Britton JR, McKeever TM. Prenatal and passive smoke exposure and incidence of asthma and wheeze: systematic review and meta-analysis. Pediatrics. 2012 Apr;129(4):735-44

12.Tsai CH, Huang JH, Hwang BF, Lee YL. Household environmental tobacco smoke and risks of asthma, wheeze and bronchitic symptoms among childrenin Taiwan.Respir Res. 2010 Jan 29;11:11

13.Pattenden S, Antova T, Neuberger M, Nikiforov B, De Sario M, Grize L, Heinrich J, Hruba F, Janssen N, Luttmann-Gibson H, Privalova L, Rudnai P, Splichalova A, Zlotkowska R, Fletcher T . Parental smoking and children's respiratory health: independent effects of prenatal and postnatal exposure .Tob Control. 2006 Aug;15(4):294-301.

14.Chan-Yeung M, Hegele RG, Dimich-Ward H, Ferguson A, SchulzerM, Chan H, Watson W, Becker A. Early environmental determinants of asthma risk in a high-risk birth cohort. Pediatr Allergy Immunol 2008: 19: 482–489.
Sam Pattenden, Temenuga Antova, Manfred Neuberger, Bojidar Nikiforov, Manuela De Sario,
Leticia Grize, Joachim Heinrich, Frantiska Hruba, Nicole Janssen, Heike Luttmann-Gibson, Larissa
Privalova, Peter Rudnai, Anna Splichalova, Renata Zlotkowska, Tony Fletcher. Parental smoking and children’s respiratory health: Independent effects of prenatal and postnatal exposure. Tobacco Control 2006;15:294–301
Carlsen KH, Lødrup Carlsen KC.Parental smoking and childhood asthma: clinical implications. Treat Respir Med. 2005;4(5):337-46.

15.Carlsen KH, Carlsen KC. Respiratory effects of tobacco smoking on infants and young children. Paediatr Respir Rev. 2008 Mar;9(1):11-9

16.Karvonen AM, Hyvärinen A, Gehring U, Korppi M, Doekes G, Riedler J, Braun-Fahrländer C, Bitter S, Schmid S, Keski-Nisula L, Roponen M, Kaulek V, Dalphin JC, Pfefferle PI, Renz H, Büchele G, von Mutius E, Pekkanen J; PASTURE Study Group. Exposure to microbial agents in house dust and wheezing, atopic dermatitis and atopic sensitization in early childhood: a birth cohort study in rural areas.Clin Exp Allergy. 2012 Aug;42(8):1246-56.

17.Campo P, Kalra HK, Levin L, Reponen T, Olds R, Lummus ZL, Cho SH, Khurana Hershey GK, Lockey J, Villareal M, Stanforth S, Lemasters G, Bernstein DI.Influence of dog ownership and high endotoxin on wheezing and atopy during infancy. J Allergy Clin Immunol. 2006 Dec;118(6):1271-8

18.Lødrup Carlsen KC, Roll S, Carlsen KH, Mowinckel P, Wijga AH, Brunekreef B, Torrent M, Roberts G, Arshad SH, Kull I, Krämer U, von Berg A, Eller E, Høst A,Kuehni C, Spycher B, Sunyer J, Chen CM, Reich A, Asarnoj A, Puig C, Herbarth O, Mahachie John JM, Van Steen K, Willich SN, Wahn U, Lau S, Keil T; GALEN WP 1.5 ‘Birth Cohorts’ working group. Does pet ownership in infancy lead to asthma or allergy at school age? Pooled analysis of individual participant data from 11 European birth cohorts. PLoS One. 2012;7


19.Simpson A, Custovic A.Pets and the development of allergic sensitization. Curr Allergy Asthma Rep. 2005 May;5(3):212-20.


Keywords: Asthma, enviromental factors, smoking parents, Pets, wheez

Conference: 15th International Congress of Immunology (ICI), Milan, Italy, 22 Aug - 27 Aug, 2013.

Presentation Type: Abstract

Topic: Immune-mediated disease pathogenesis

Citation: Mirzaei M and Mirzaei M (2013). The prevalence of wheezing and its relationship with some environmental factors in children aged 6-7 in Yazd. Front. Immunol. Conference Abstract: 15th International Congress of Immunology (ICI). doi: 10.3389/conf.fimmu.2013.02.00486

Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters.

The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated.

Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed.

For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions.

Received: 16 Apr 2013; Published Online: 22 Aug 2013.

* Correspondence:
Mr. Mojtaba Mirzaei, Tehran University of Medical Sciences and Health Care, Tehran, Iran, mojtaba.mirzaei.87@gmail.com
Dr. Mohsen Mirzaei, Yazd University Of Medical Sciences and Health Care, Yazd, Iran, drmirzaee@yahoo.com