Up- down state switching in a conductance - based cortex model
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1
University of Lübeck, Institute for Neuro- and Bioinformatics, Germany
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2
University of Lübeck, Plasticity and Sleep, Germany
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3
University of Lübeck, Graduate School for Computing in Medicine and Life Science, Germany
A recent experiment [1] investigated the on- and off switching of bursting activity in ferret brain slices. This experiment is seen as a paradigmatic system towards the understanding of the emergence of cortical slow waves. The basic dynamics can be modeled by a simplified discretized integrate-and-fire model including inhibitory currents [2]. Here we use a conductance-based model to reproduce the spike-burst dynamics and the triggering of on-states as obeserved in [1].
References
1 Shu, Y., Hasenstaub, A. & McCormick, D.A. Turning on and off recurrent balanced cortical activity. Nature 423, 288-293 (2003).
2 Ngo, H.V., Köhler, J., Mayer, J., Claussen, J.C. & Schuster, H.G. Triggering up states in all-to-all coupled neurons. Europhys. Lett. 89, 68002 (2010).
Keywords:
computational neuroscience
Conference:
Bernstein Conference on Computational Neuroscience, Berlin, Germany, 27 Sep - 1 Oct, 2010.
Presentation Type:
Poster Abstract
Topic:
Bernstein Conference on Computational Neuroscience
Citation:
Weigenand
A,
Ngo
H,
Higgins
DC,
Martinetz
T and
Claussen
J
(2010). Up- down state switching in a conductance - based cortex model.
Front. Comput. Neurosci.
Conference Abstract:
Bernstein Conference on Computational Neuroscience.
doi: 10.3389/conf.fncom.2010.51.00138
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Received:
24 Sep 2010;
Published Online:
24 Sep 2010.
*
Correspondence:
Mr. Arne Weigenand, University of Lübeck, Institute for Neuro- and Bioinformatics, Lübeck, Germany, a.w.weigenand@gmx.net