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Using QEEG parameters (asymmetry, coherence, and P3a Novelty response) to track improvement in the treatment of depression.

Leon Petchkovsky1*, Kirstin Robertson-Gillam2 and Yury Kropotov3
  • 1 University of Queensland, Department of Psychiatry, Australia
  • 2 University of Western Sydney, Psychology, Australia
  • 3 Institute of the Human Brain of The Russian Academy of Sciences, Russia

This pilot study reports the findings from a sub-group of 9 patients, from a cohort of 30 middle-aged ambulant depressive patients undergoing an intensive 8 week choral singing programme, who received “before” and “after” QEEGs (resting state and the WinEEG VCPT ERP protocol). “Before” and “after” mental state examinations and Beck Depressive Inventory showed significant improvement (10 point score drop, p< 0.0001). Group spectral analysis of resting QEEG showed greater L/R hemispheric symmetry of activity, reduction of right polar pre-frontal hyper activity, and reduction of hypercoherence (all reported depressive parameters).
ERP results revealed that an initially heightened P3a Novelty Cingulate Gyrus response reduced significantly over the course of treatment (p<0.05).

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Keywords: qEEG, Depression, hypercoherence, P3a Novelty, right frontal activity

Conference: ACNS-2012 Australasian Cognitive Neuroscience Conference, Brisbane, Australia, 29 Nov - 2 Dec, 2012.

Presentation Type: Poster Presentation

Topic: Emotion and Social

Citation: Petchkovsky L, Robertson-Gillam K and Kropotov Y (2012). Using QEEG parameters (asymmetry, coherence, and P3a Novelty response) to track improvement in the treatment of depression.. Conference Abstract: ACNS-2012 Australasian Cognitive Neuroscience Conference. doi: 10.3389/conf.fnhum.2012.208.00097

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Received: 25 Oct 2012; Published Online: 07 Nov 2012.

* Correspondence: Prof. Leon Petchkovsky, University of Queensland, Department of Psychiatry, TERRANORA, NSW, 2486, Australia, leon.petchkovsky@gmail.com