Large scale database of normal adult magnetocardiogram
Akihiko
Kandori1*,
Kuniomi
Ogata1,
Tsuyoshi
Miyashita1,
Yasuyoshi
Watanabe2,
Kimio
Tanaka2,
Masahiro
Murakami3,
Yuji
Oka2,
Hiroshi
Takaki4,
Syuji
Hashimoto4,
Yuko
Yamada4,
Kazuo
Komamura4,
Wataru
Shimizu4,
Shiro
Kamakura4,
Shigeyuki
Watanabe5 and
Kazutaka
Aonuma5
-
1
Hitachi Ltd., Advanced Research Laboratory, Japan
-
2
Hitachi General Hospital, Japan
-
3
Hitachi High-Technologies Corporation, Japan
-
4
National Cardiovascular Center, Japan
-
5
Tsukuba University, Japan
Background: The magnetocardiogram (MCG) is a new non-contact medical tool for detecting and visualizing cardiac electrical activation in the heart. To determine the abnormalities in the heart disease patients using MCG, we have produced a large-scale MCG database [1] and a standard MCG waveform [2] of healthy subjects. In this presentation, we have summarized MCG features regarding to the gender and age-related influences. Methods We measured 869 MCG data (male: 554 subjects; female: 315) using a conventional 64-channel MCG system, which covers the whole heart. Out of 869 subjects, 464 people (male: 268, female: 196) were identified and analyzed as a normal group using ECG data. Time intervals (PQ, QRS, QT, and QTc), current distributions (maximum current vector (MCV), and the total current vector (TCV)) of MCG data of the 464 normal subjects were analyzed to obtain basic MCG parameters. Furthermore, the measured data were averaged after shortening or lengthening and normalization to produce a standard MCG waveform. Results Although mean values of PQ and QRS intervals of the male subjects were slightly longer than those of the female subjects, no intervals were correlated with gender or age. The correlation between PQ intervals of ECG and those of MCG was better than the correlation between QRS and QT intervals of ECG and those of MCG. Both MCV and TCV angles were much smaller than the electrical-axis angle in ECG. The produced standard waveform had a typical QRS-complex shape in six regions. Conclusion The large-scale MCG database provides a normal range for MCG and the basic knowledge of MCG features.
References
1. Kandori A, et al., Space-time database for standardization of adult magnetocardiogram- Making standard MCG parameters Pacing and Clinical Electrophysiology, 2008 Apr;31(4):422-31.
2. Kandori A, et al., Standard template of adult magnetocardiogram, Annals of Noninvasive Electrocardiology, 2008;13(4):390–399.
Conference:
Biomag 2010 - 17th International Conference on Biomagnetism , Dubrovnik, Croatia, 28 Mar - 1 Apr, 2010.
Presentation Type:
Oral Presentation
Topic:
MCG: Instrumentation, Modeling, Basic and Clinical Studies
Citation:
Kandori
A,
Ogata
K,
Miyashita
T,
Watanabe
Y,
Tanaka
K,
Murakami
M,
Oka
Y,
Takaki
H,
Hashimoto
S,
Yamada
Y,
Komamura
K,
Shimizu
W,
Kamakura
S,
Watanabe
S and
Aonuma
K
(2010). Large scale database of normal adult magnetocardiogram.
Front. Neurosci.
Conference Abstract:
Biomag 2010 - 17th International Conference on Biomagnetism .
doi: 10.3389/conf.fnins.2010.06.00310
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Received:
06 Apr 2010;
Published Online:
06 Apr 2010.
*
Correspondence:
Akihiko Kandori, Hitachi Ltd., Advanced Research Laboratory, Tokyo, Japan, akihiko.kandori.vc@hitachi.com