Event Abstract

Workshop: tractography-based dissections of language networks

  • 1 King's College London, Neuroimaging, United Kingdom
  • 2 King's College London, Forensics and Neurodevelopmental Sciences, United Kingdom

Until recently, measuring and visualising white matter connections was limited to invasive or post mortem methods. The recent development of tractography methods based on diffusion imaging is offering the possibility of mapping macroscopic and microscopic properties of the white matter pathways in the living human brain. The workshop will provide an introduction to methods that we have developed to study the anatomy of the major associative connections. These include the three segments of the arcuate fasciculus (Catani et al., 2005), the frontal aslant tract (Catani et al., 2013), and the ventral occipito-temporal-frontal pathways (Forkel 2014; Catani et al., 2003; D’Anna et al., 2016). The workshop will provide a hands-on training on virtual in-vivo dissections of white matter pathways in the human brain whilst also touching upon pre-processing and processing of diffusion data. Participants are invited to bring their own laptops and perform virtual dissections on a provided training dataset. Demonstrative examples of tract dissections will be performed on healthy brains, stroke, and primary progressive aphasia datasets. Presentations: Connectional anatomy of language and the basics of tractography presented by Stephanie Forkel Introduction to tractography software for analysis presented by Henrietta Howells Connectional anatomy of perisylvian language pathways – Arcuate Fasciculus presented by Stephanie Forkel, Naianna Robertsson, Claudia Cramer, Henrietta Howells Connectional anatomy of the extended language network – ventral occipito-temporal-frontal pathways presented by Henrietta Howells, Naianna Robertsson, Claudia Cramer, Stephanie Forkel


Catani, M., Jones, D. K., Donato, R., & ffytche, D. H. (2003). Occipito-temporal connections in the human brain. Brain, 126, 2093–2107.

Catani, M., Jones, D. K., & ffytche, D. H. (2005). Perisylvian language networks of the human brain. Ann Neurol., 57, 8–16.

Catani, M., Mesulam, M. M., Jakobsen, E., Malik, A., Wieneke, C., Thompson, C. K., Thiebaut de Schotten, M., Dell'Acqua, F., Weintraube, S., & Rogalski, E. (2013). A novel frontal pathway underlies verbal fluency in primary progressive aphasia. Brain, 136, 2619–2628.

D'Anna, L., Mesulam, M. M., Thiebaut de Schotten, M., Dell'Acqua, F., Murphy, D., Wieneke, C., Martersteck, A., Cobie, D., Rogalski, E., & Catani, M. (2016). Frontotemporal networks and behavioral symptoms in primary progressive aphasia. Neurology, doi:10.1212/WNL.0000000000002579.

Forkel, S. J., Thiebaut de Schotten, M., Dell'Acqua, F., Kalra, L., Murphy, D. G. M., Williams, S. C. R. & Catani, M. (2014). Anatomical predictors of aphasia recovery: a tractography study of bilateral perisylvian language networks. Brain, 137, 2027–2039.

Forkel, S. J., Thiebaut de Schotten, M., Kawadler, J., Dell'Acqua, F., Danek, A., & Catani, M. (2014). The anatomy of fronto-occipital connections from early blunt dissections to contemporary tractography. Cortex, 56, 73–84.

Keywords: tractography, white matter, Neuroanatomy, Neuroimaging, Language, Aphasia

Conference: 54th Annual Academy of Aphasia Meeting, Llandudno, United Kingdom, 16 Oct - 18 Oct, 2016.

Presentation Type: Mini-workshop

Topic: Academy of Aphasia

Citation: Forkel SJ, Robertsson N, Cramer C and Howells H (2016). Workshop: tractography-based dissections of language networks. Front. Psychol. Conference Abstract: 54th Annual Academy of Aphasia Meeting. doi: 10.3389/conf.fpsyg.2016.68.00118

Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters.

The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated.

Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed.

For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions.

Received: 30 Apr 2016; Published Online: 15 Aug 2016.

* Correspondence: Dr. Stephanie J Forkel, King's College London, Neuroimaging, London, SE58AF, United Kingdom, stephanie.forkel@kcl.ac.uk