NPI and MMSE: Do they correlate?
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1
Dokuz Eylül University, Türkiye
Background: The Mini Mental State Examination (MMSE) is a global cognitive scale that also gives information about the clinical stage. The Neuropsychiatric Inventory (NPI) is widely used for assessment of behavioral symptoms.
Objective: To assess behavioral symptoms in different stages of Turkish AD subjects.
Methods: We gathered data from referral centers using a Turkish web-based dementia registry. MMSE and NPI scores were elicited from all subjects. We compared scores of total and 10 NPI subitems across MMSE groups. Also we compared NPI results from all centers. Repeated measures of ANOVA for post-hoc Bonferroni were perforrmed.
Results: In this multicenter study, using a Turkish web-based dementia registry, a total of 217 probable AD subjects were assessed. The mean age was 73.66 years (SE: 0.59). The number of subjects across the MMSE stages were 68 in early, 100 in moderate, and 49 in severe stages. Among these MMSE groups total NPI scores differed (F=21.05, p=0.000), but NPI distress scores were not different (F=9.12, p=0.106). In the correlational analyses, a strong correlation between total NPI (r=-0.51, P=0.000), MMSE scores in the educated and a moderate correlation in the uneducated (r=-0.284, P=0.032) were found. Among the centers, the total NPI distress score changed, but not the total NPI score.
Discussion: Our findings imply that behavioral symptoms increase along with advancing stages of AD. Centers from different regions of Turkey showed variability in caregiver distress scores. Also Turkish version of NPI can be used reliably across the centers from the different regions of Turkey.
Conference:
10th International Conference on Cognitive Neuroscience, Bodrum, Türkiye, 1 Sep - 5 Sep, 2008.
Presentation Type:
Oral Presentation
Topic:
Cognitive Aging
Citation:
Yener
G
(2008). NPI and MMSE: Do they correlate?.
Conference Abstract:
10th International Conference on Cognitive Neuroscience.
doi: 10.3389/conf.neuro.09.2009.01.166
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Received:
08 Dec 2008;
Published Online:
08 Dec 2008.
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Correspondence:
Gorsev Yener, Dokuz Eylül University, Izmir, Türkiye, gorsev.yener@gmail.com