Event Abstract

Individual-subject activations of the posterior frontolateral cortex in a task-switching paradigm

  • 1 Max Planck Institute for Neurological Research, Germany
  • 2 Ghent University, Belgium
  • 3 Max Planck Institute for Human Cognitive and Brain Sciences, Germany
  • 4 Institute of Neurosciences and Biophysics 3 (Medicine), Germany
  • 5 RWTH Aachen University, Germany

The sulcal morphology of the human frontal lobe is highly variable. Although the structural images usually acquired in functional magnetic resonance imaging (fMRI) studies provide information about this interindividual variability, this information is only rarely used to relate structure and function. We investigated the spatial relationship between posterior frontolateral activations in a task-switching paradigm and the junction of the inferior frontal sulcus and the inferior precentral sulcus (IFJ) on an individual-subject basis using volume-based thresholding. Results show that, although variable in terms of stereotaxic coordinates, the posterior frontolateral activations observed in task-switching are consistently and reliably located at the IFJ in the brains of individual participants. The IFJ shares such consistent localization with other non-primary areas as motion-sensitive area V5/MT and the frontal eye field. Building on tension-based models of morphogenesis, this structure-function correspondence might indicate that the cytoarchitectonic area underlying activations of the IFJ develops at early stages of cortical folding.

Conference: 10th International Conference on Cognitive Neuroscience, Bodrum, Turkey, 1 Sep - 5 Sep, 2008.

Presentation Type: Poster Presentation

Topic: Decision Making and Response Selection

Citation: Derrfuss J, Brass M, Von Cramon D, Lohmann G and Amunts K (2008). Individual-subject activations of the posterior frontolateral cortex in a task-switching paradigm. Front. Hum. Neurosci. Conference Abstract: 10th International Conference on Cognitive Neuroscience. doi: 10.3389/conf.neuro.09.2009.01.193

Received: 08 Dec 2008; Published Online: 08 Dec 2008.

* Correspondence: Jan Derrfuss, Max Planck Institute for Neurological Research, Cologne, Germany, jan.derrfuss@nf.mpg.de

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