Genotoxicity of indium tin oxide by comet test
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1
Afyon Kocatepe University, Molecular Biology and Genetics, Türkiye
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2
Usak University, Molecular Biology and Genetics, Türkiye
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3
Üsküdar University, Molecular Biology and Genetics, Türkiye
Indium tin oxide (ITO) is used for liquid crystal display (LCDs), electrochromic displays, flat panel displays, field emission displays, touch or laptop computer screens, cell phones, energy conserving architectural windows, defogging aircraft and automobile windows, heat-reflecting coatings to increase light bulb efficiency, gas sensors, antistatic window coatings, wear resistant layers on glass, nanowires and nanorods because of its unique properties of high electrical conductivity, transparency and mechanical resistance.Genotoxic effects of ITO were investigated on the root cells of Allium cepa by Comet assay. A. cepa roots were treated with the aqueous dispersions of ITO at 5 different concentrations (12.5, 25, 50, 75, and 100 ppm) for 4 h. A significant increase in DNA damage was a observed at all concentrations of ITO by Comet assay. These result indicate that ITO exhibit genotoxic activity in A. cepa root meristematic cells.
Keywords:
Allium,
Comet Assay,
DNA Damage,
Indium Tin Oxide,
Genotoxicity
Conference:
ICAW 2015 - 11th International Comet Assay Workshop, Antwerpen, Belgium, 1 Sep - 4 Sep, 2015.
Presentation Type:
Poster Presentation
Topic:
Genotoxicity testing of chemicals and nanomaterials
Citation:
Ciğerci
İH,
Liman
R,
Özgül
E and
Konuk
M
(2015). Genotoxicity of indium tin oxide by comet test.
Front. Genet.
Conference Abstract:
ICAW 2015 - 11th International Comet Assay Workshop.
doi: 10.3389/conf.fgene.2015.01.00040
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Received:
13 May 2015;
Published Online:
23 Jun 2015.
*
Correspondence:
Prof. Muhsin Konuk, Üsküdar University, Molecular Biology and Genetics, İstanbul, Türkiye, mkonuk@gmail.com