The endocannabinoid system and the regulation of memory for emotionally arousing experiences
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1
Università degli Studi di Roma La Sapienza, Physiology and Pharmacology, Italy
The activation of neuromodulatory systems affecting the amygdala and its projections to other brain regions, plays a key role in enabling emotionally significant experiences to be well remembered. Although it is vital for a human being to be able to remember emotionally arousing experiences, the efficient encoding of emotional memories can, in certain conditions, become maladaptive. Indeed, severe stress often turns emotional memories into a source of chronic anxiety, which may lead to the development of stress related disorders. In this talk I will present the results of studies that addressed the effects induced by the manipulation of the endocannabinoid system in the modulation of memory for emotional experiences. I will focus on the role of the endocannabinoid system in the modulation of memory consolidation for emotionally arousing experiences, showing how this system interacts with other neuromodulatory systems in the regulation of such processes.
Keywords:
endocannabinoid system,
learning and memory,
emotional arousal,
Rats,
Glucocorticoids
Conference:
4th Conference of the Mediterrarnean Neuroscience Society, Istanbul, Türkiye, 30 Sep - 3 Oct, 2012.
Presentation Type:
Symposium
Topic:
Abstracts
Citation:
Campolongo
P
(2013). The endocannabinoid system and the regulation of memory for emotionally arousing experiences.
Conference Abstract:
4th Conference of the Mediterrarnean Neuroscience Society.
doi: 10.3389/conf.fnhum.2013.210.00012
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Received:
26 Jan 2013;
Published Online:
11 Apr 2013.
*
Correspondence:
Dr. Patrizia Campolongo, Università degli Studi di Roma La Sapienza, Physiology and Pharmacology, Rome, 00159, Italy, Patrizia.Campolongo@uniroma1.it