Treatment of white lesion of the oral cavity with laser therapy: a case series
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1
University of Milano-Bicocca, Department of Medicine and Surgery, Italy
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2
University of Ferrara, Department of Morphology, Experimental Medicine and Surgery, Italy
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3
Department of Psychology, University of Campania 'Luigi Vanvitelli, Multidisciplinary Department of Medical-Surgical and Dental Specialties, Italy
Aim.
The aim of this study is to perform a laser-assisted protocol as less invasive as possible to be offered to patients.
Materials and Methods.
20 patients were included in this study, of which 9 were affected by hyperkeratosis and 11 were affected by leukoplakia. The sample consisted of 11 men (55%) with an average age of 55 years old and 9 women (45%) with an average age of 67 years old, the average age of the sample was of 61 years old. A diode laser which wavelength was 940 nm, the fiber had a length of 9 mm and diameter of 300 microns was used; a pulsed mode was selected with a Ton corresponding to Toff and corresponding to 10-3 seconds, the period corresponds to the summary of Ton and Toff that is 2x10-3 seconds. The treatment consisted of four sessions a week and a follow-up visit one month after the last treatment session. The following data were collected before treatment, and in the final follow-up session:
• The measure of the lesion.
• The appearance of the lesion.
• The discomfort of the lesion measured with an arbitrary numerical scale from 0 to 5.
• The pain caused by the lesion measured, with an NRS scale (Numerical Rating Scale, Downie, 1978; Grossi, 1983),
• The tactile perception, that is the sensation of roughness that the patient felt passing the tongue on the area where the lesion was present, with an arbitrary numerical scale from 0 to 5.
Results.
Dimension of lesion: the dimension between the two-time intervals was reduced by an average of 40%. Discomfort analysis: the perception of the discomfort caused by laser therapy resulted approximate to zero. Pain: no patient reported pain during therapeutic treatment. Tactile perception: there is a significant reduction in tactile perception.
Discussion.
In conclusion we can state that the treatment is a valid alternative to conventional surgery with scalpel if the lesion has a size greater than 8 mm, below this limit it is better to completely eliminate the lesion during biopsy. From what has been observed, lesions with a maximum size of 2 cm can regress during the four sessions set: obviously the larger the lesion, the more time needed to allow the lesion to regress.
References
1. PG. Ardiuno, J. Bagan, AK El-Naggar, M. Carrozzo, “Urban legends series: Oral Leukoplakia”, in Oral Disease, 19, 2013, pp 642- 659.
2. A. Kumar, L. Cascarini J. McCaul, C. J. Kerawala, D. Coombed, D. Godden, P. A. Brennan, “How should we manage oral leukoplakia?”, in BRITISH journal of oral and maxillofacial surgery,51, 2013, pp 377-383.
3. L. Monteiro, C. Barbieri, M. Martins, F. Salazar, P. Vescovi, M. Meleti, J. Pacheco, “Type of surgical treatment and recurrence of oral leukoplakia: A retrospective clinical study”, in Oral Medicine and Pathology, 22, 2017 ,pp 520-526.
Keywords:
Adenocarcinoma,
Lung carcinoma,
Oral metastasis,
Primary cancer,
Upper jaw
Conference:
5th National and 1st International Symposium of Italian Society of Oral Pathology and Medicine., Ancona, Italy, 19 Oct - 20 Oct, 2018.
Presentation Type:
Poster Presentation
Topic:
Oral Diseases
Citation:
Gabrione
F,
Oberti
L,
Candotto
V,
Lucchese
A,
Carinci
F and
Lauritano
D
(2019). Treatment of white lesion of the oral cavity with laser therapy: a case series.
Front. Physiol.
Conference Abstract:
5th National and 1st International Symposium of Italian Society of Oral Pathology and Medicine..
doi: 10.3389/conf.fphys.2019.27.00002
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Received:
11 Oct 2018;
Published Online:
09 Dec 2019.
*
Correspondence:
Dr. Federica Gabrione, University of Milano-Bicocca, Department of Medicine and Surgery, Milan, Lombardy, 20126, Italy, f.gabrione@campus.unimib.it