Statistical Approaches, Applications, and Software for LongitudinalMicrobiome Data Analysis and Microbiome Multi-Omics Data Integration

Yuan Jiang, Jun Chen, Huilin Li, Mogens Fenger

Frontiers Media SA

Statistical methods play a pivotal role in analyzing longitudinal microbiome data and integrating...

Science Genetics Statistical Genetics and Methodology

Keywords: Statistical approaches,­applications,­Longitudinal Microbiome Data analysis,­Micro-biome,­multi-omnics dataintegration

Rare Diseases Research and Diagnosis in Low- and Middle-Income Countries

Claudia Gonzaga-Jauregui, Vajira Dissanayake, Ferran Casals, Aradhana Dwivedi, Kawmadi Gunawardena

Frontiers Media SA

Rare diseases (RDs) encompass more than 7000 described disorders characterized by a low prevalence...

Science Genetics Genetics of Common and Rare Diseases

Keywords: Rare Diseases,­LMICs,­Genomic sequencing,­Developing Countries,­genetic disorders

The Role of the Tumor Microenvironment (TME) and relevant Novel Biomarkers in Oncogenesis, 2nd edition

Zhouxiao Li, Hongyong Cao, Wei Xu

Frontiers Media SA

Tumors and their surroundings are closely related and constantly interact. Tumors can influence...

Science Genetics Cancer Genetics

Keywords: Tumor Microenvironment,­tumor immunity,­target therapy,­bioinformatics,­Predict and Prognosis Model

High-throughput Sequencing-based Investigation of Chronic Disease Markers and Mechanisms, volume II

Hua Li, Wen-Lian Chen, Yuriy L. Orlov, Guoshuai Cai

Frontiers Media SA

This Research Topic is part of a series of:...

Science Genetics Human and Medical Genomics

Keywords: high-throughput sequencing,­biomarker development,­Chronic Disease,­Omics study,­disease mechanism

Proficiency testing in Histocompatibility and Immunogenetics: current status and future perspectives

Kelley M. K. Hitchman, Martin Petrek, Milena Vraná, Jose Palacio-Gruber

Frontiers Media SA

Proficiency testing (PT) has been part of Immunogenetics since its early days. Starting from...

Science Genetics Immunogenetics

Keywords: Histocompatibility,­Immunogenetic Tests,­Quality control,­HLA-typing,­Chimerism testing,­cross-match,­HLA-antibody identification

Mendelian Randomization: the Study of Causal Relationships between Tumors and Underlying Pathogenic Factors

Ziheng Wang, Guangsheng Pei

Frontiers Media SA

The malignant tumor is a major global public health problem threatening human health. At present,...

Science Genetics Statistical Genetics and Methodology

Keywords: Mendelian randomization,­oncology,­GWAS,­randomized controlled trials,­phenotype,­Genotype

Mendelian Randomization: An Approach for Precision Medicine and Public Health

Triinu Peters, Xiaoqing Pan, Yi-Ju Li, Jiayue-Clara Jiang

Frontiers Media SA

Epidemiological studies have established various observational associations between modifiable...

Science Genetics Statistical Genetics and Methodology

Keywords: Mendelian randomization,­ Epidemiological studies,­ Mendel’s laws,­ genome-wide association studies (GWAS)

Understanding Molecular Mechanisms to Facilitate the Development of Biomarkers for Therapeutic Intervention in Gastrointestinal Diseases and Sepsis

Dipak Kumar Sahoo, Romy Monika Heilmann, Ashish Patel

Frontiers Media SA

This research topic aims to provide an overview of the most recent advancements in understanding...

Science Genetics Human and Medical Genomics

Keywords: gastrointestinal disorders,­Sepsis,­miRNA; ,­biomarkers;,­epigenetics;,­inflammatory bowel disease,­antimicrobial resistance,­One Health,­Cancer

Data governance in African health research: ELSI challenges and solutions

Donrich Thaldar, Simisola Oluwatoyin Akintola, Bonginkosi Shozi

Frontiers Media SA

Data protection legislation is increasingly being enacted in African countries. Additionally, the...

Science Genetics ELSI in Science and Genetics

Keywords: Data governance,­ELSI,­Africa,­health research,­Africanisation,­decolonisation,­rule-harmonisation,­Informed Consent,­Trust,­Multi-dimensional,­Regulation authority,­AI