The Role of Ubiquitination in Disease Development, Progression, and Prognosis

Wenyi Jin, Mario Hiroyuki Hirata

Frontiers Media SA

Ubiquitination, an essential post-translational modification, controls various cellular functions...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Ubiquitination,­tumor cells,­Immune Regulation,­disease development,­disease progression,­Disease prognosis,­Tumor Microenvironment

Advancements and Cutting-Edge Approaches to Counteract the Inefficacy of Immune Checkpoint Inhibitor Therapies in Lung Cancer

Guangchun Han, Guangsheng Pei, Ziheng Wang

Frontiers Media SA

Lung cancer is among the cancers with the highest incidence in the world, of which about 80% of...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Immune checkpoint inhibitor,­lung cancer,­programmed death receptor 1(PD-1),­programmed death ligand 1(PD-L1),­Tcell mucin immunoglobulin 3(TIM-3)

Crosstalk in Ferroptosis, Immunity & Inflammation

Qi Feng, Hua Zhong, Yu’e Liu

Frontiers Media SA

Ferroptosis represents a critical form of regulated cell death, notable for its reliance on iron...

Health Immunology Inflammation

Keywords: ferroptosis,­Inflammation,­Immunity,­Lipid Metabolism,­Inflammatory diseases,­Cancer,­Targeted drugs,­targeted drugs tumor immunosuppressive niche,­Immunotherapy,­chemotherapy

Unraveling the Molecular Mechanisms of Cytokine Signaling in Regulating Inflammatory Diseases

Wai Po Chong, Jian Zheng, Huawei Mao

Frontiers Media SA

Chronic and dysregulated inflammation play a significant role in the pathogenesis of autoimmune...

Health Immunology Cytokines and Soluble Mediators in Immunity

Keywords: Cytokin,­Inflammation,­Autoimmunity,­Infection - immunology,­signaling pathway

Epigenetics in the microbiome-host crosstalk: from mechanisms to Therapeutics

Chengfei Liu, Wenda Wu, Haoyu Liu, Hui-Xin Liu, Omar Ramos-Lopez

Frontiers Media SA

Epigenetic modifications allow cells to change gene expression without altering the genetic code,...

Health Immunology Microbial Immunology

Keywords: Dysbiosis,­epigenetic,­Bacteria,­microbiota

Long COVID and Brain Inflammation: Unravelling Mechanisms and Potential Therapies

Fatemeh Saheb Sharif-Askari, Karem Alzoubi, Jacob Raber

Frontiers Media SA

COVID-19, an illness caused by the novel coronavirus SARS-CoV-2, has affected millions of people...

Health Immunology Inflammation

Keywords: Long Covid,­Brain inflammation,­Neuroinflammation,­SARS-CoV-2,­mechanisms,­Pathogenesis,­Symptoms,­Imaging studies,­therapy,­Treatment

Unveiling Biomarkers and Mechanisms in the Tumor-Immune Nexus

Wantao Wu, Pengpeng Zhang, Jiaheng Xie, Uday Kishore

Frontiers Media SA

The interplay between cancer cells and the immune system is a critical area of research, with...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Immunotherapy Response Biomarkers,­Tumor-immune interactions,­Immune evasion mechanisms,­Tumor Microenvironment,­Next-generation sequencing technologies,­single-cell RNA sequencing,­cancer immunology,­Therapeutic Targets in Immunotherapy

Immunological Precision Therapeutics: Integrating Multi-Omics Technologies and Comprehensive Approaches for Personalized Immune Intervention

Wenyi Jin, Raquel Alarcon Rodriguez, Mar Requena Mullor

Frontiers Media SA

In the realm of modern immunology, the pursuit of precision therapeutics has emerged as a paramount...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Immunotherapy,­precision medicine,­Multi-omics analysis,­immune signatures,­personalized therapy

Methods in Molecular Innate Immunity: 2022

Carrie Ambler, Jorg Hermann Fritz, Thomas A. Kufer

Frontiers Media SA

This Research Topic is part of the “Methods in Immunology” series. Please submit your article to...

Health Immunology Molecular Innate Immunity

Keywords: innate immunity,­Inflammation,­methods,­innate lymphoid cells,­Myeloid Cells