Investigating the Interplay Between Tumor Mutations, Immune Evasion, and Targeted Therapy Resistance

Shanye Yin, Guangchuang Yu, Yinghao Wu

Frontiers Media SA

The field of cancer research has been significantly focused on understanding the complex interplay...

Health Oncology Molecular and Cellular Oncology

Keywords: tumor mutations,­Immune Evasion,­Targeted therapy resistance,­tumor heterogeneity,­Tumor Microenvironment,­Cancer Progression,­tumor-associated neoantigens

Deciphering the Role of Signature Genes in Cancer Prognosis and Therapy Resistance

Dalila Luciola Zanette, Manoj K. Pandey, Jawed A. Siddiqui

Frontiers Media SA

The field of signature genes in cancer prognosis and therapy resistance is pivotal in the...

Health Oncology Molecular and Cellular Oncology

Keywords: Gene expression signature,­tumor molecular subtypes,­molecular pathways,­resistance mechanisms,­targeted therapy

Integrating Health-Related Quality of Life in Neuro-Oncology

Maria Teresa Pedro, Peter Hau, Carolin Weiss Lucas, Christine Jungk, Martina Messing-Jünger

Frontiers Media SA

Health-Related Quality of Life (HRQoL) in neuro-oncological patients is a complex and multifaceted...

Health Oncology Neuro-Oncology and Neurosurgical Oncology

Keywords: health-related quality of life,­HRQOL,­neuro-oncological diseases,­precision medicine,­personalized treatment,­Adult patients,­Central Nervous System,­Peripheral Nervous System

Treatment of Brain Metastases from Non-Small Cell Lung Cancer: Preclinical, Clinical, and Translational Research

Lin Zhou, Jianxin Xue, Lei Deng

Frontiers Media SA

Non-small cell lung cancer (NSCLC) is the most common malignancy worldwide, with up to 50% of...

Health Oncology Thoracic Oncology

Keywords: brain metastases,­Non-small cell lung cancer,­Therapeutic modalities,­clinical studies,­Molecular mechanisms

Radiotherapy for Head and Neck Cancers

Xinyuan Chen, Minglei Kang, Jun-Lin Yi

Frontiers Media SA

Radiotherapy is a crucial treatment modality for head and neck cancers, encompassing a range of...

Health Oncology Radiation Oncology

Keywords: Radiotherapy,­head and neck cancers,­Radiobiology,­Computed tomography (CT),­magnetic resonance imaging (MRI),­positron emission tomography (PET)

Breast Cancer Imaging: Clinical Translation of Novel Methods

Jiabao He, Luca Nicosia, Sai Man Cheung, Simone Palma

Frontiers Media SA

Breast cancer has become the most common cancer in women, and the incidence rate has increased by...

Health Oncology Cancer Imaging and Image-directed Interventions

Keywords: MR imaging,­Nuclear Medicine,­clinical translation,­breast cancer,­imaging,­translational

Genomics and Epigenomics of Cancer Immunotherapy: Challenges and Clinical Implications, 3rd edition

Xiao-Jie Lu, Malak Abedalthagafi, Xiaochen Wang

Frontiers Media SA

Cancer immunotherapy aims to activate, boost or normalize the immune system to attack cancer cells...

Health Oncology

Keywords: Antitumor immunogenicity,­personalized biomarkers,­Immunotherapy combinations,­preclinical models,­Immune cell dysfunction

Oncogenic PI3KT/Akt/mTOR Pathway Alterations, ROS Homeostasis, Targeted Cancer therapy and drug resistance, 2nd edition

Rozangela Curi Pedrosa, Karina Felipe, Danilo Wilhelm Filho

Frontiers Media SA

The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin...

Health Oncology

Keywords: PI3KT,­Akt,­mTOR,­Metabolism,­Reactive Oxygen Species

Allogenic Hematopoietic Cell Transplant in Hematological Malignancies: Controversies and Perspective

Salvatore Leotta, Jacopo Mariotti, Sabrina Giammarco

Frontiers Media SA

The Allogeneic Hematopoietic Stem Cell Transplantation (HSCT), since the experiments in rodents in...

Health Oncology Hematologic Malignancies

Keywords: Stem Cell Transplantation,­Acute leukemia,­graft versus host disease,­hematological malignancies,­Conditioning regimen