Formation of Immunological Niches in Tumor Microenvironments: Mechanisms and Therapeutic Potential

Ying Luo, Weiling Li, Qingyu Luo, Xiaosheng Tan, Yabing Nan

Frontiers Media SA

The tumor microenvironment (TME) plays a pivotal role in cancer progression and response to...

Health Oncology Molecular and Cellular Oncology

Keywords: Tumor Microenvironment,­immunological niches,­Immune Evasion,­Immunotherapy,­Cytokines,­Chemokines,­Stromal Cells,­biomarkers,­therapeutic targets,­personalized medicine

The Role of Post-translational Modifications in Cancer Biology

Arun Kumar Trivedi, Swati Srivastava, Anurag Tripathi

Frontiers Media SA

Post translational modifications (PTMs) of a protein significantly impact on its structure and...

Health Oncology Molecular and Cellular Oncology

Keywords: post-translational modifications,­Ubiquitination,­Methylation,­Phosphorylation,­Sumoylation

Repurposed Drugs Targeting Cancer Signaling Pathways: Clinical Insights to Improve Oncologic Therapies, volume II

Gerardo Leyva-Gómez, Teresita Padilla-Benavides, Alma D. Campos-Parra

Frontiers Media SA

The field of drug development is a time-consuming and costly process, with the development of...

Health Oncology Molecular and Cellular Oncology

Keywords: Drug Repositioning,­Cancer,­Signaling Pathways,­treatments

Investigating the Interplay Between Tumor Mutations, Immune Evasion, and Targeted Therapy Resistance

Shanye Yin, Guangchuang Yu, Yinghao Wu

Frontiers Media SA

The field of cancer research has been significantly focused on understanding the complex interplay...

Health Oncology Molecular and Cellular Oncology

Keywords: tumor mutations,­Immune Evasion,­Targeted therapy resistance,­tumor heterogeneity,­Tumor Microenvironment,­Cancer Progression,­tumor-associated neoantigens

Deciphering the Role of Signature Genes in Cancer Prognosis and Therapy Resistance

Dalila Luciola Zanette, Manoj K. Pandey, Jawed A. Siddiqui

Frontiers Media SA

The field of signature genes in cancer prognosis and therapy resistance is pivotal in the...

Health Oncology Molecular and Cellular Oncology

Keywords: Gene expression signature,­tumor molecular subtypes,­molecular pathways,­resistance mechanisms,­targeted therapy

Advances in the Molecular Mechanisms in Gastrointestinal Tumorigenesis and Treatment

Ruowen Zhang, XiuJuan Qu, Yu Zhang

Frontiers Media SA

Gastrointestinal (GI) cancer, the group of cancers that affect the gastrointestinal tract and other...

Health Oncology Molecular and Cellular Oncology

Keywords: gastrointestinal cancer,­molecular oncology,­metastasis,­therapeutic resistance,­Novel therapy

Advances in the Molecular Mechanisms in Gastrointestinal Tumorigenesis and Treatment

Ruowen Zhang, XiuJuan Qu, Yu Zhang

Frontiers Media SA

Gastrointestinal (GI) cancer, the group of cancers that affect the gastrointestinal tract and other...

Health Oncology Molecular and Cellular Oncology

Keywords: gastrointestinal cancer,­molecular oncology,­metastasis,­therapeutic resistance,­Novel therapy

Evolutionary Biology of Tumor Initiation and Progression

Yusuke Suenaga, Erich Bornberg-Bauer, Mamoru Kato

Frontiers Media SA

Cancer is characterized by heterogeneous cells with capacity for self renewal, and selective...

Health Oncology Molecular and Cellular Oncology

Keywords: cancer evolution,­cancer heterogeneity,­Comparative Oncology,­cancer immunity,­Cancer genomics,­de novo evolved gene,­single-cell sequencing

New Insights into Fibrotic Signaling in Cancer

Patrick Ming-Kuen Tang, Eric W-F Lam, Francis Jay Mussai, Dongmei Zhang, Chunjie Li

Frontiers Media SA

Cancer is still a top leading cause of death worldwide. Ineffective treatments, severe side...

Health Oncology Molecular and Cellular Oncology