Advances in Molecular and Pharmacological Mechanisms of Novel Targeted Therapies for Melanoma

Luana Mota Ferreira, Marcel Henrique Marcondes Sari, Juliana Hofstatter Azambuja

Frontiers Media SA

Malignant melanoma is the most aggressive type of skin cancer with invasive growth patterns. Recent...

Health Oncology Pharmacology of Anti-Cancer Drugs

Keywords: Skin Cancer,­Melanoma,­immunology,­Nanotechnology,­Cancer biomarkers,­Drug repositining,­Immunotherapy

Oncogenic PI3KT/Akt/mTOR Pathway Alterations, ROS Homeostasis, Targeted Cancertherapy and drug resistance

Rozangela Curi Pedrosa, Karina Felipe, Danilo Wilhelm Filho

Frontiers Media SA

The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin...

Health Oncology Pharmacology of Anti-Cancer Drugs

Keywords: PI3KT/Akt/mTOR Pathway,­Metabolism,­Reactive Oxygen Species

Adaptive Immune Resistance in Cancer Therapy

Lin Qi, Ouyang Chen, Zhigang Liu, Hongzhou Cai

Frontiers Media SA

The adaptive immune resistance (AIR) mechanism refers to the various strategies employed by tumours...

Science Pharmacology Pharmacology of Anti-Cancer Drugs

Keywords: adaptive immune resistance,­Immune Evasion,­Immunotherapy,­cancer therapy

Immunotherapy and multimodality therapy for lung cancer

Qun Xue, Jie Mei, Zichao Luo, Wenjun Mao, Yuan Wan, Yifei Liu

Frontiers Media SA

Health Medicine

Overcoming Physiologic Barriers to Treatments for Hematologic Malignancies by Molecularly Targeting the Tumor Microenvironment

Qin Wang, Lili Feng, Arif Gulzar, Chen Wang, Yang-Bao Miao

Frontiers Media SA

Hematologic malignancies (HMs) represent a group of hematologic cancers originating from bone...

Science Pharmacology Pharmacology of Anti-Cancer Drugs

Keywords: Hematologic malignancy,­physiologic barrier,­Anti-tumor therapy,­Tumor Microenvironment

The Role of Tumor Microenvironment in the Development, Treatment and Prognosis of Hepatocellular Carcinoma

Zhigang Ren, Jiang Chen, Xuming Tang, Hui Liu

Frontiers Media SA

Primary liver cancer (PLC), including hepatocellular carcinoma (HCC) and intrahepatic...

Science Pharmacology Pharmacology of Anti-Cancer Drugs

Keywords: Hepatocellular Carcinoma,­Tumor Microenvironment,­therapy resistance,­Metabolic microenvironment,­immune microenvironment

Multi-targeted Natural Products as Cancer Therapeutics: Challenges and Opportunities, Volume I, 2nd edition

Jiang-Jiang Qin, Wei-Dong Zhang, Huizi Jin, Sanjay K. Srivastava

Frontiers Media SA

Cancer remains a leading cause of disease-related deaths worldwide, despite recent advances in our...

Health

Keywords: Natural Products,­Traditional Chinese Medicine,­Multi-targeting Mechanisms,­Cancer Prevention and Therapy,­Folk remedies

Molecular Mechanisms of Drug Resistance And Strategies of Sensitization in Breast Cancer. 2nd edition

Yan Cheng, Jin-Ming Yang, Ceshi Chen, Yi Zhang

Frontiers Media SA

Basic scientific background Breast cancer is one of the most common cancer and the most frequent...

Health

Keywords: breast cancer,­Drug Resistance,­Molecular mechanisms,­sensitization strategies,­Reverse resistance

Evolution of Phytochemicals and Phytotherapies in the Treatment and Management of Cancer: Targeted Strategies in Cancer Precision Medicine

Mohd Adnan, Mitesh Patel, Visweswara Rao Pasupuleti

Frontiers Media SA

There is a rising recurrence of cancers in humans and related complications of chemotherapeutic...

Science Pharmacology Pharmacology of Anti-Cancer Drugs

Keywords: Phytotherapy,­precision oncology,­Drug Discovery,­secondary metabolites,­cancer therapeutics