AUTHOR=Hucka Michael , Nickerson David P. , Bader Gary D. , Bergmann Frank T. , Cooper Jonathan , Demir Emek , Garny Alan , Golebiewski Martin , Myers Chris J. , Schreiber Falk , Waltemath Dagmar , Le Novère Nicolas TITLE=Promoting Coordinated Development of Community-Based Information Standards for Modeling in Biology: The COMBINE Initiative JOURNAL=Frontiers in Bioengineering and Biotechnology VOLUME=3 YEAR=2015 URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2015.00019 DOI=10.3389/fbioe.2015.00019 ISSN=2296-4185 ABSTRACT=

The Computational Modeling in Biology Network (COMBINE) is a consortium of groups involved in the development of open community standards and formats used in computational modeling in biology. COMBINE’s aim is to act as a coordinator, facilitator, and resource for different standardization efforts whose domains of use cover related areas of the computational biology space. In this perspective article, we summarize COMBINE, its general organization, and the community standards and other efforts involved in it. Our goals are to help guide readers toward standards that may be suitable for their research activities, as well as to direct interested readers to relevant communities where they can best expect to receive assistance in how to develop interoperable computational models.