AUTHOR=Uppal Karan , Soltow Quinlyn A. , Promislow Daniel E. L. , Wachtman Lynn M. , Quyyumi Arshed Ali , Jones Dean P. 

TITLE=MetabNet: An R Package for Metabolic Association Analysis of High-Resolution Metabolomics Data

JOURNAL=Frontiers in Bioengineering and Biotechnology

VOLUME=3

YEAR=2015

URL=https://www.frontiersin.org/journals/bioengineering-and-biotechnology/articles/10.3389/fbioe.2015.00087

DOI=10.3389/fbioe.2015.00087

ISSN=2296-4185

ABSTRACT=<p>Liquid-chromatography high-resolution mass spectrometry provides capability to measure &gt;40,000 ions derived from metabolites in biologic samples. This presents challenges to confirm identities of known chemicals and delineate potential metabolic pathway associations of unidentified chemicals. We provide an R package for metabolic network analysis, MetabNet, to perform targeted metabolome-wide association study of specific metabolites to facilitate detection of their related metabolic pathways and network structures.</p>