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REVIEW article

Front. Bioeng. Biotechnol., 19 November 2021
Sec. Nanobiotechnology
Volume 9 - 2021 | https://doi.org/10.3389/fbioe.2021.775309

Optimizing sgRNA to Improve CRISPR/Cas9 Knockout Efficiency: Special Focus on Human and Animal Cell

www.frontiersin.orgSadegh Shojaei Baghini1 www.frontiersin.orgZhanna R. Gardanova2,3 www.frontiersin.orgAngelina Olegovna Zekiy4 www.frontiersin.orgNavid Shomali5 www.frontiersin.orgFoad Tosan6* www.frontiersin.orgMostafa Jarahian7*
  • 1Plant Biotechnology Department, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran
  • 2Department of Psychotherapy, Pirogov Russian National Research Medical University, Moscow, Russia
  • 3Medical Faculty, Russian State Social University, Moscow, Russia
  • 4Department of Prosthetic Dentistry, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
  • 5Immunology Research Center (IRC), Tabriz University of Medical Sciences, Tabriz, Iran
  • 6Student Research Committee, Semnan University of Medical Sciences, Semnan, Iran
  • 7German Cancer Research Center, Toxicology and Chemotherapy Unit (G401), Heidelberg, Germany
This article has been retracted. Please follow the link to the full retraction notice for details.

Citation: Shojaei Baghini S, Gardanova ZR, Zekiy AO, Shomali N, Tosan F and Jarahian M (2021) Optimizing sgRNA to Improve CRISPR/Cas9 Knockout Efficiency: Special Focus on Human and Animal Cell. Front. Bioeng. Biotechnol. 9:775309. doi: 10.3389/fbioe.2021.775309

Received: 13 September 2021; Accepted: 26 October 2021;
Published: 19 November 2021; Retracted: 04 September 2023.

Edited by:

Mina Sarani, Zabol University of Medical Sciences, Iran

Reviewed by:

Mahmood Barani, Shahid Bahonar University of Kerman, Iran
Shakeel Ahmad, Ayub Agricultural Research Institute, Pakistan
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