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REVIEW article

Front. Cell Dev. Biol.
Sec. Epigenomics and Epigenetics
Volume 12 - 2024 | doi: 10.3389/fcell.2024.1397788

Non-coding RNAs and Exosomal non-coding RNAs in Lung cancer: Insights into their functions Provisionally Accepted

Xiaolong Lv1 Lei Yang2 Yunbo Xie3  Mohammad Reza Momeni4*
  • 1The Peoples Hospital of Langfang City, China
  • 2People's Hospital of Tongliang District, China
  • 3First Affiliated Hospital of Chongqing Medical University, China
  • 4Tehran University of Medical Sciences, Iran

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Lung cancer is the second most common form of cancer worldwide Research points to the pivotal role of non-coding RNAs (ncRNAs) in controlling and managing the pathology by controlling essential pathways. ncRNAs have all been identified as being either up- or downregulated among individuals suffering from lung cancer thus hinting that they may play a role in either promoting or suppressing the spread of the disease. Several ncRNAs could be effective non-invasive biomarkers to diagnose or even serve as effective treatment options for those with lung cancer, and several molecules have emerged as potential targets of interest. Given that ncRNAs are contained in exosomes and are implicated in the development and progression of the malady. Herein, we have summarized the role of ncRNAs in lung cancer. Moreover, we highlight the role of exosomal ncRNAs in lung cancer.

Keywords: lung cancer, non-coding RNA, microRNA, long non-coding RNA, circular RNA

Received: 08 Mar 2024; Accepted: 02 May 2024.

Copyright: © 2024 Lv, Yang, Xie and Momeni. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Dr. Mohammad Reza Momeni, Tehran University of Medical Sciences, Tehran, Iran