TY - JOUR AU - Ashikari, Yosuke AU - Tamaki, Takashi AU - Takahashi, Yusuke AU - Yao, Yiyue AU - Atobe, Mahito AU - Nagaki, Aiichiro PY - 2022 M3 - Original Research TI - Investigation of Parameter Control for Electrocatalytic Semihydrogenation in a Proton-Exchange Membrane Reactor Utilizing Bayesian Optimization JO - Frontiers in Chemical Engineering UR - https://www.frontiersin.org/articles/10.3389/fceng.2021.819752 VL - 3 SN - 2673-2718 N2 - Owing to its applicability in sustainable engineering, flow electrochemical synthesis in a proton-exchange membrane (PEM) reactor has attracted considerable attention. Because the reactions in PEM reactors are performed under electro-organic and flow-synthetic conditions, a higher number of reaction parameters exist compared to ordinary reactions. Thus, the optimization of such reactions requires significant amounts of energy, time, chemical and human resources. Herein, we show that the optimization of alkyne semihydrogenation in PEM reactors can be facilitated by means of Bayesian optimization, an applied mathematics strategy. Applying the optimized conditions, we also demonstrate the generation of a deuterated Z-alkene. ER -