AUTHOR=Tu Yaoquan TITLE=Computational studies of DNA sequencing with solid-state nanopores: key issues and future prospects JOURNAL=Frontiers in Chemistry VOLUME=2 YEAR=2014 URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2014.00005 DOI=10.3389/fchem.2014.00005 ISSN=2296-2646 ABSTRACT=

Owing to the potential use for real personalized genome sequencing, DNA sequencing with solid-state nanopores has been investigated intensively in recent time. However, the area still confronts problems and challenges. In this work, we present a brief overview of computational studies of key issues in DNA sequencing with solid-state nanopores by addressing the progress made in the last few years. We also highlight future challenges and prospects for DNA sequencing using this technology.