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Front. Chem. | doi: 10.3389/fchem.2018.00038

Silicon nanomaterials for biosensing and bioimaging analysis

 Xiaoyuan Ji1, Houyu Wang1, Bin Song1, Binbin Chu1 and  Yao He1*
  • 1Soochow University, China

Biochemical analysis in reliable, low-toxicity, and real-time manners are essentially important for exploring and unraveling biological events and related mechanisms. Silicon nanomaterial-based sensors and probes have potentiality to satisfy the above-mentioned requirements. Herein, we present an overview of the recent significant improvement in large-scale and facile synthesis of high-quality silicon nanomaterials and the research progress of biosensing and bioimaging analysis based on silicon nanomaterials. We especially illustrate the advanced applications of silicon nanomaterials in the field of ultrasensitive biomolecular detection and dynamic biological imaging analysis, with a focus on real-time and long-term detection. In the final section of this review, we discuss the major challenges and promising development in this domain.

Keywords: Silicon, nanomaterials, Synthesis, biosensing, bioimaging

Received: 06 Dec 2017; Accepted: 14 Feb 2018.

Edited by:

Xiaomin Li, Fudan University, China

Reviewed by:

Yiqing Lu, Macquarie University, Australia
Ruoxue Yan, University of California, Riverside, United States
Xiaoji Xie, Nanjing Tech University, China  

Copyright: © 2018 Ji, Wang, Song, Chu and He. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Prof. Yao He, Soochow University, Suzhou, China, yaohe@suda.edu.cn