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Original Research ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Chem. | doi: 10.3389/fchem.2019.00154

Supramolecular fluorescence probe based on twisted cucurbit[14]uril for sensing fungicide flusilazole

Ying Fan1, Ruihan Gao1, Ying Huang1, Bing Bian2, Tao Zhu1* and  Xin Xiao1*
  • 1Guizhou University, China
  • 2Shandong University of Science and Technology, China

The host-guest complex of the common dye, thioflavin T (ThT) and twisted cucurbit[14]uril (tQ[14]) was selected as a fluorescent probe to determine non-fluorescent triazole fungicides, including flusilazole, azaconazole, triadimefon, tebuconazole, tricyclazole, flutriafol, penconazole, and triadimenol isomer A, in an aqueous solution. The experimental results reveal that the ThT@tQ[14] probe selectively responded to flusilazole with significant fluorescence quenching and a detection limit of 1.27 × 10−8 mol/L. In addition, the response mechanism involves not only a cooperation interaction¾ThT occupies a side-cavity of the tQ[14] host and the triazole fungicide occupies another side-cavity of the tQ[14] host—but also a competition interaction in which both ThT and the triazole fungicide occupy the side-cavities of the tQ[14] host.

Keywords: Twisted cucurbit[14]uril, thioflavin T, Fluorescent probe, Triazole fungicides, Flusilazole

Received: 30 Aug 2018; Accepted: 01 Mar 2019.

Edited by:

Angela Casini, Cardiff University, United Kingdom

Reviewed by:

Simin Liu, Wuhan University of Science and Technology, China
Dong-Sheng Guo, Nankai University, China  

Copyright: © 2019 Fan, Gao, Huang, Bian, Zhu and Xiao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Prof. Tao Zhu, Guizhou University, Guiyang, China, gzutao@263.net
Prof. Xin Xiao, Guizhou University, Guiyang, China, gyhxxiaoxin@163.com