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Review ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Chem. | doi: 10.3389/fchem.2019.00697

New perspectives for fisetin

 Oleg Demchuk1* and Grzegorz Grynkiewicz Grynkiewicz1*
  • 1Instytut Farmaceutyczny, Poland

Fisetin is a flavonol that shares distinct antioxidant properties with a plethora of other plant polyphenols. Additionally, it exhibits a specific biological activity of considerable interest as regards the protection of functional macromolecules against stress which results in the sustenance of normal cells cytoprotection. Moreover, it shows potential as an anti-inflammatory, chemopreventive, chemotherapeutic and recently also senotherapeutic agent. In view of its prospective applications in healthcare and likely demand for fisetin , methods for its preparation and their suitability for pharmaceutical use are discussed herein.

Keywords: Fisetin, Flavon-3-ols, Synthesis of flavonols, Biological activity of flavonols, anti-cancer, anti-ageing

Received: 23 Jul 2019; Accepted: 08 Oct 2019.

Copyright: © 2019 Demchuk and Grynkiewicz. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Prof. Oleg Demchuk, Instytut Farmaceutyczny, Warsaw, Poland, oleg_demchuk@hotmail.com
Prof. Grzegorz Grynkiewicz Grynkiewicz, Instytut Farmaceutyczny, Warsaw, Poland, grynicz@gmail.com