@ARTICLE{10.3389/fchem.2020.00818, AUTHOR={Yuan, Ye and Wang, Liping and Gao, Lizeng}, TITLE={Nano-Sized Iron Sulfide: Structure, Synthesis, Properties, and Biomedical Applications}, JOURNAL={Frontiers in Chemistry}, VOLUME={8}, YEAR={2020}, URL={https://www.frontiersin.org/articles/10.3389/fchem.2020.00818}, DOI={10.3389/fchem.2020.00818}, ISSN={2296-2646}, ABSTRACT={Nano-sized iron sulfides have attracted intense research interest due to the variety of their types, structures, and physicochemical properties. In particular, nano-sized iron sulfides exhibit enzyme-like activity by mimicking natural enzymes that depend on an iron-sulfur cluster as cofactor, extending their potential for applications in biomedicine. The present review principally summarizes the synthesis, properties and applications in biomedical fields, demonstrating that nano-sized iron sulfides have considerable potential for improving human health and quality of life.} }