AUTHOR=Bischoff Markus , Wonnenberg Bodo , Nippe Nadine , Nyffenegger-Jann Naja J. , Voss Meike , Beisswenger Christoph , Sunderkötter Cord , Molle Virginie , Dinh Quoc Thai , Lammert Frank , Bals Robert , Herrmann Mathias , Somerville Greg A. , Tschernig Thomas , Gaupp Rosmarie TITLE=CcpA Affects Infectivity of Staphylococcus aureus in a Hyperglycemic Environment JOURNAL=Frontiers in Cellular and Infection Microbiology VOLUME=7 YEAR=2017 URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2017.00172 DOI=10.3389/fcimb.2017.00172 ISSN=2235-2988 ABSTRACT=
Many bacteria regulate the expression of virulence factors via carbon catabolite responsive elements. In Gram-positive bacteria, the predominant mediator of carbon catabolite repression is the catabolite control protein A (CcpA). Hyperglycemia is a widespread disorder that predisposes individuals to an array of symptoms and an increased risk of infections. In hyperglycemic individuals, the bacterium