AUTHOR=Huhn Evelyn A., Rossi Simona W., Hoesli Irene, Göbl Christian S. TITLE=Controversies in Screening and Diagnostic Criteria for Gestational Diabetes in Early and Late Pregnancy JOURNAL=Frontiers in Endocrinology VOLUME=9 YEAR=2018 URL=https://www.frontiersin.org/articles/10.3389/fendo.2018.00696 DOI=10.3389/fendo.2018.00696 ISSN=1664-2392 ABSTRACT=This review serves to evaluate the screening and diagnostic strategies for gestational diabetes and overt diabetes in pregnancy. We focus on the different early screening and diagnostic approaches in first trimester including fasting plasma glucose, random plasma glucose, oral glucose tolerance test, hemoglobin A1c, risk prediction models and biomarkers. Early screening for gestational diabetes is currently not recommended since the potential benefits and harms of early detection and subsequent treatment need to be further evaluated in randomized controlled trials.