AUTHOR=Qin Guo-Qiang , Chen Li , Zheng Jun , Wu Xiao-Min , Li Yang , Yang Kai , Liu Tong-Feng , Fang Zhong-Ze , Zhang Qiang 

TITLE=Effect of passive smoking exposure on risk of type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies

JOURNAL=Frontiers in Endocrinology

VOLUME=Volume 14 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2023.1195354

DOI=10.3389/fendo.2023.1195354

ISSN=1664-2392

ABSTRACT=Objective: The effect of passive smoking exposure on the risk of type 2 diabetes has not been systematically studied. A meta-analysis was conducted to assess the association between passive smoking exposure and the risk of diabetes.Methods: We searched three major databases up to 31 October 2022 to identify relevant prospective cohort studies on the association between passive smoking and the risk of type 2 diabetes. The pooled relative risk (RR) and 95% confidence interval (CI) for the association between passive smoking exposure and the risk of type 2 diabetes were analyzed using a fixed effect model. Results: 10 prospective cohort studies were included in this meta-analysis, with a total of 251,620 participants involved. The pooled RR showed a significantly positive association between nonsmokers exposed to passive smoking and type 2 diabetes as compared to non-smokers who were not exposed to passive smoking (RR = 1.27, 95% CI [1.19, 1.36]; p < 0.001). Sensitivity analysis indicated that the pooled RR was not substantially affected by any of the individual studies.Exposure to passive smoking increases the risk of type 2 diabetes. This study may have a positive effect on the prevention of type 2 diabetes.