AUTHOR=Abghari Ali , Chen Shulin 

TITLE=Yarrowia lipolytica as an Oleaginous Cell Factory Platform for Production of Fatty Acid-Based Biofuel and Bioproducts

JOURNAL=Frontiers in Energy Research

VOLUME=2

YEAR=2014

URL=https://www.frontiersin.org/journals/energy-research/articles/10.3389/fenrg.2014.00021

DOI=10.3389/fenrg.2014.00021

ISSN=2296-598X

ABSTRACT=<p>Today’s biotechnologists seek new biocatalysts to meet the growing demand for the bioproducts. This review critically evaluates the potential use of <italic>Y. lipolytica</italic> as an oleaginous cell factory platform. This yeast has undergone extensive modifications for converting a wide range of hydrophobic and hydrophilic biomass, including alkane, oil, glycerol, and sugars to fatty acid-based products. This article highlights challenges in the development of this platform and provides an overview of strategies to enhance its potential in the sustainable production of biodiesel, functional dietary lipid compounds, and other value-added oleochemical compounds. Future applications of the recombinant <italic>Y. lipolytica</italic> platform are also discussed.</p>