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CORRECTION article

Front. Immunol., 21 February 2020 | https://doi.org/10.3389/fimmu.2020.00277

Corrigendum: Natural Killer Cell-Derived Exosomal miR-3607-3p Inhibits Pancreatic Cancer Progression by Targeting IL-26

Hongwei Sun1, Keqing Shi2, Kai Qi3, Hongru Kong1, Jie Zhang1, Shengjie Dai1, Wen Ye1, Tuo Deng1, Qiye He4,5 and Mengtao Zhou6*
  • 1Department of Hepatobiliary Surgery, Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of ZheJiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
  • 2Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of ZheJiang Province, Center of Precision Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
  • 3Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China
  • 4Singlera Genomics Inc., San Diego, CA, United States
  • 5Singlera Genomics (Shanghai) Ltd., Shanghai, China
  • 6Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of ZheJiang Province, Precision Medical Center Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

A Corrigendum on
Natural Killer Cell-Derived Exosomal miR-3607-3p Inhibits Pancreatic Cancer Progression by Targeting IL-26

by Sun, H., Shi, K., Qi, K., Kong, H., Zhang, J., Dai, S., et al. (2019). Front. Immunol. 10:2819. doi: 10.3389/fimmu.2019.02819

In the original article, there was a mistake in Figure 1 and Figure 5 as published. Figures 1E and Figure 5F were wrongly placed. The corrected Figure 1 and Figure 5 appears below.

FIGURE 1
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Figure 1. NK cells co-culture inhibited tumor progression of pancreatic cancer both in vitro and in vivo. (A,B) CCK-8 assay showed cell viability of Mia PaCa-2 and PANC-1 cells co-cultured with (NK cells+) or without (NK cells-) natural killer cells. (C) Colony formation assay showed cell proliferation of Mia PaCa-2 and PANC-1 cells co-cultured with (NK cells+) or without (NK cells-) natural killer cells. (D,E) Transwell assays showed cell migratory and invasive ability of Mia PaCa-2 and PANC-1 cells co-cultured with (NK cells+) or without (NK cells-) natural killer cells. (F,G) PANC-1 cells were implanted into the flank of mice (n = 4 each group), without (NK cell−) or with co-injection of natural killer cells (NK cell+), respectively, followed by growth curve evaluation on the indicated day after injection. (H–J) Representative in vivo images showed tumor colonization in the lungs of mice (n = 5 each group) following tail vein injection of PANC-1 cells, without (NK cell−) or with co-injection of natural killer cells (NK cell+), respectively, H&E staining of lung sections of mice (metastatic nodules were indicated by yellow arrow, 200×) and incidence of lung metastasis in mice following tail vein injection of the respective PANC-1 cells. The data represent the mean ± SD from three independent experiments. **P < 0.01; ***P < 0.001, two-way ANOVA for (A,B,G), χ2 test for j, Student's t-test for others.

FIGURE 5
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Figure 5. MiR-3607-3p suppressed proliferation, migration and invasion of pancreatic cancer cells. (A) Mia PaCa-2 and PANC-1 cells were transfected with miR-3607-3p mimics (miR-3607-3p) or mimics negative control (miR-NC), miR-3607-3p expression levels were quantified by qRT-PCR analysis. (B,C) CCK-8 assay showed cell viability of Mia PaCa-2 and PANC-1 cells transfected with miR-3607-3p mimics (miR-3607-3p) or mimics negative control (miR-NC). (D) Colony formation assay showed cell proliferation of Mia PaCa-2 and PANC-1 cells transfected with miR-3607-3p mimics (miR-3607-3p) or mimics negative control (miR-NC). (E,F) Transwell assays showed cell migratory and invasive ability of Mia PaCa-2 and PANC-1 cells transfected with miR-3607-3p mimics (miR-3607-3p) or mimics negative control (miR-NC). The data represent the mean ± SD from three independent experiments. **P < 0.01; ***P < 0.001. Two-way ANOVA for b and c, Student's t-test for others.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Keywords: natural killer, pancreatic cancer, extracellular vesicles, miR-3607-3p, IL-26

Citation: Sun H, Shi K, Qi K, Kong H, Zhang J, Dai S, Ye W, Deng T, He Q and Zhou M (2020) Corrigendum: Natural Killer Cell-Derived Exosomal miR-3607-3p Inhibits Pancreatic Cancer Progression by Targeting IL-26. Front. Immunol. 11:277. doi: 10.3389/fimmu.2020.00277

Received: 01 January 2020; Accepted: 04 February 2020;
Published: 21 February 2020.

Edited and reviewed by: Katy Rezvani, University of Texas MD Anderson Cancer Center, United States

Copyright © 2020 Sun, Shi, Qi, Kong, Zhang, Dai, Ye, Deng, He and Zhou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Mengtao Zhou, qianazi@yeah.net

These authors have contributed equally to this work