TY - JOUR AU - Ayona, Diyoly AU - Fournier, Pierre-Edouard AU - Henrissat, Bernard AU - Desnues, Benoit PY - 2020 M3 - Review TI - Utilization of Galectins by Pathogens for Infection JO - Frontiers in Immunology UR - https://www.frontiersin.org/articles/10.3389/fimmu.2020.01877 VL - 11 SN - 1664-3224 N2 - Galectins are glycan-binding proteins which are expressed by many different cell types and secreted extracellularly. These molecules are well-known regulators of immune responses and involved in a broad range of cellular and pathophysiological functions. During infections, host galectins can either avoid or facilitate infections by interacting with host cells- and/or pathogen-derived glycoconjugates and less commonly, with proteins. Some pathogens also express self-produced galectins to interfere with host immune responses. This review summarizes pathogens which take advantage of host- or pathogen-produced galectins to establish the infection. ER -