TY - JOUR AU - Ali, Ayesha AU - Tan, HuiYing AU - Kaiko, Gerard E. PY - 2020 M3 - Review TI - Role of the Intestinal Epithelium and Its Interaction With the Microbiota in Food Allergy JO - Frontiers in Immunology UR - https://www.frontiersin.org/articles/10.3389/fimmu.2020.604054 VL - 11 SN - 1664-3224 N2 - The intestinal epithelial tract forms a dynamic lining of the digestive system consisting of a range of epithelial cell sub-types with diverse functions fulfilling specific niches. The intestinal epithelium is more than just a physical barrier regulating nutrient uptake, rather it plays a critical role in homeostasis through its intrinsic innate immune function, pivotal regulation of antigen sensitization, and a bi-directional interplay with the microbiota that evolves with age. In this review we will discuss these functions of the epithelium in the context of food allergy. ER -