TY - JOUR AU - Hu, Mengyan AU - Liu, Sanxin AU - Lu, Danli AU - Zhong, Yi AU - Yu, Dafan AU - Qiu, Wei AU - Lu, Zhengqi AU - Zhang, Bingjun PY - 2021 M3 - Case Report TI - Case Report: Central Nervous System Immune Reconstitution Inflammatory Syndrome Related to Bacterial Meningitis JO - Frontiers in Immunology UR - https://www.frontiersin.org/articles/10.3389/fimmu.2021.585316 VL - 12 SN - 1664-3224 N2 - Central nervous system immune reconstitution inflammatory syndrome (CNS-IRIS) describes clinical characteristics that may be observed in previously immunocompromised patients during rapid restoration of immunity function in the presence of a pathogen. There have been no reports about CNS-IRIS related to bacterial meningitis so far. Here, we report a 24-year-old pregnant female patient with bacterial meningitis. Her clinical and neuroradiological condition worsened after induced labor despite great effective anti-infective therapy. CNS-IRIS was considered. Corticosteroids were administered, and the patient gradually recovered. We present the first case of CNS-IRIS associated with bacterial meningitis. ER -