TY - JOUR AU - Yang, Keda AU - Wen, Guangfu AU - Wang, Jinpeng AU - Zhou, Siming AU - Da, Wacili AU - Meng, Yan AU - Xue, Yuchuan AU - Tao, Lin PY - 2021 M3 - Original Research TI - Complication and Sequelae of COVID-19: What Should We Pay Attention to in the Post-Epidemic Era JO - Frontiers in Immunology UR - https://www.frontiersin.org/articles/10.3389/fimmu.2021.711741 VL - 12 SN - 1664-3224 N2 - COVID-19 is widespread worldwide and seriously affects the daily life and health of humans. Countries around the world are taking necessary measures to curb the spread. However, COVID-19 patients often have at least one organ complication and sequelae in addition to respiratory symptoms. Controlling the epidemic is only a phased victory, and the complication and sequelae of COVID-19 will need more attention in the post-epidemic era. We collected general information from over 1000 articles published in 2020 after the COVID-19 outbreak and systematically analyzed the complication and sequelae associated with eight major systems in COVID-19 patients caused by ACE2 intervention in the RAS regulatory axis. The autoimmune response induced by 2019-nCoV attacks and damages the normal tissues and organs of the body. Our research will help medical workers worldwide address COVID-19 complication and sequelae. ER -