AUTHOR=Terra Luciana , Abreu Paula A. , Teixeira Valéria L. , Paixão Izabel C. P. , Pereira Rebeca , Leal Bruno , Lourenço André Luiz , Rampelotto Pabulo H. , Castro Helena C. 

TITLE=Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products

JOURNAL=Frontiers in Marine Science

VOLUME=1

YEAR=2014

URL=https://www.frontiersin.org/journals/marine-science/articles/10.3389/fmars.2014.00012

DOI=10.3389/fmars.2014.00012

ISSN=2296-7745

ABSTRACT=<p>Currently, the limited number of antifungals available for treating fungal infections, the increased multiresistance, and the adverse effects are the major obstacles for fungal infection therapy. Additionally, the recent emergence of opportunistic fungus infections reinforced the requirement for discovering novel antifungal agents. Herein we reviewed the main topics about fungi and its related infections, the antifungals available, their mechanism of action and resistance profile. In this work, we pointed fungi as a biotechnological target for finding new options in alternative sources such as marine products with new mechanisms of action to allow treating these dangerous infections.</p>