AUTHOR=Sattar Saud Bin Abdul , Iqbal Qasim Zafar , Haider Muhammad Adnan , Zia Zeeshan , Niazi Muhammad Raphay Khan , Hanif Muhammad , Ali Mukarram Jamat , Khan Muhammad Aslam TITLE=Locked-in Syndrome in a Young Patient Due to SARS-CoV-2: A Case Report JOURNAL=Frontiers in Medicine VOLUME=7 YEAR=2020 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2020.574690 DOI=10.3389/fmed.2020.574690 ISSN=2296-858X ABSTRACT=

Coronavirus disease 2019 (COVID-19), apart from commonly involving the respiratory system, has its impact on the central nervous system, with a wide spectrum of clinical presentations ranging from headaches to ischemic strokes. The ongoing research regarding this novel disease has found that there is a very high prevalence of thrombotic episodes especially in critically ill patients when compared to severe presentation of other viral illnesses. This COVID-19-associated coagulopathy has a very complex etiology with the ability to form thrombus in arteries, veins, and microvasculatures of different organs. We present a unique case of a young woman with underlying COVID-19 who unfortunately developed locked-in syndrome due to bilateral pontine infarction during the course of her illness.