AUTHOR=Kilic Hatice , Arguder Emine , Karalezli Aysegul , Unsal Ebru , Guner Rahmet , Kayaslan Bircan , Hasanoglu İmran , Ates İhsan , Civak Musa , Akpınar Esmehan , Parlak Ebru , Sadi Filiz , Kocaman Yasin , Günay Sibel , Metan Esra , Er Mukremin , Dalkıran Aynil , Hezer Habibe , Ergüden Hülya , Hancıoğlu Zeynep , Kalem Ayşe , Eser Fatma , Aypak Adalet , Akıncı Esragül , Karahmetoğlu Selma , Gemcioglu Emin , Kalkan Emra , İnan Osman , Yilmaz Abdulrezzak , Güler Bagdagul , Çopuroğlu Esra , Turan İşil , Gökmen Derya , Hayme Serhat , Surel Aziz Ahmet
TITLE=Effect of chronic lung diseases on mortality of prevariant COVID-19 pneumonia patients
JOURNAL=Frontiers in Medicine
VOLUME=9
YEAR=2022
URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.957598
DOI=10.3389/fmed.2022.957598
ISSN=2296-858X
ABSTRACT=BackgroundThe aim of the study is to assess the effect of chronic lung disease on mortality in patients hospitalized with the diagnosis of prevariant COVID-19 Pneumonia compared to patients without chronic lung disease.
Research design and methodsA cohort of 1,549 patients admitted to the pandemic clinic with a COVID-19 Pneumonia diagnosis was analyzed. Group 1 and Group 2 were compared in terms of the treatment they received, admission to intensive care, mortality and follow-up parameters.
ResultsThe patient group with COVID-19 and lung disease consisted of 231 participants (14.91%) (Group 1). The patient group with COVID-19 but without lung disease had 1,318 participants (85.19%). Group 1 cases were found to receive more oxygen therapy and mechanical ventilation than Group 2 cases (p ≤ 0.001), Following univariate and multiple logistic regression analyses, it was determined that patients with chronic lung disease had a 25.76% higher mortality risk [OR: 25.763, 95% CI (Lower-Upper) (2.445–271.465), p = 0.007].
ConclusionIt was found that chronic lung disease contributed significantly to mortality in this study. Among chronic lung diseases, Chronic Obstructive Pulmonary Disease (COPD), lung cancer and interstitial lung diseases (ILDs) were shown to be more effective than other chronic lung diseases in patients with prevariant COVİD-19 population.